53087-13-1

Basic information

• Product Name: 3-BENZYLOXYBROMOBENZENE
• Synonyms: 1-BENZYLOXY-3-BROMOBENZENE;3-BROMOPHENYL BENZYL ETHER;3-BENZYLOXYBROMOBENZENE;BENZYL 3-BROMOPHENYL ETHER;3-Benzyloxybromobenzen;1-Bromo-3-benzyloxybenzene;1-Benzyloxy-3-broMobenzene,Benzyl 3-BroMophenyl Ether
• CAS NO: 53087-13-1
• Molecular Formula: C₁₃H₁₁BrO
• Molecular Weight: 263.13
• EINECS: 1308068-626-2
• Product Categories: Phenetole;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;Ethers;Organic Building Blocks;Oxygen Compounds;alkyl bromide
• Mol File: 53087-13-1.mol
• Article Data: 43

Chemical Properties

• Melting Point: 62°C
• Boiling Point: 333.5 °C at 760 mmHg
• Flash Point: 137.6 °C
• Appearance: White/Solid
• Density: 1.382 g/cm³
• Vapor Pressure: 0.000264mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-BENZYLOXYBROMOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYLOXYBROMOBENZENE(53087-13-1)
• EPA Substance Registry System: 3-BENZYLOXYBROMOBENZENE(53087-13-1)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/37/38-50/53-43-41
• Safety Statements: 26-36/37/39-50/53-43-41-61-60
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 53087-13-1(Hazardous Substances Data)

Usage

Chemical Properties

Whitetolightyellowcrystalpowde

InChI:InChI=1/C13H11BrO/c14-12-7-4-8-13(9-12)15-10-11-5-2-1-3-6-11/h1-9H,10H2

Upstream product

• 591-20-8 3-Bromophenol 
• 100-44-7 benzyl chloride 
• 585-79-5 m-nitrobromobenzene 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 584-08-7 potassium carbonate 
• 89598-96-9 (3-bromophenyl)boronic acid 

Downstream Products

• 122294-02-4 methyl 3'-(benzyloxy)-[1,1'-biphenyl]-4-carboxylate 
• 132630-71-8 (+/-)-trans-tetrahydro-3-<(dimethylamino)methyl>-4-<3-(phenylmethoxy)phenyl>-2H-pyran-4-ol hydrochloride 
• 133776-44-0 (2-aminophenyl)(3-benzyloxyphenyl)methanone 
• 440105-54-4 [3-(benzyloxy)phenyl](3-chlorophenyl)methanol 
• 1053647-77-0 1-benzyloxy-3-[3',5'-O-((1,1,3,3-tetraisopropyl)disiloxandiyl)-2'-deoxy-β-D-ribofuranosyl]benzene 
• 320727-36-4 1-(3'-benzyloxyphenyl)ethanol 
• 156682-54-1 3-(benzyloxy)phenylboronic acid 
• 757961-91-4 (3-benzyloxy-phenyl)-(3,5-dimethoxy-phenyl)-methanol 
• 954271-22-8 3-benzyloxy-benzenesulfonamide 
• 26926-56-7 4-(3-benzyloxy-phenyl)-morpholine 
• 893736-53-3 3'-benzyloxy-biphenyl-3-carboxylic acid methyl ester 
• 893736-89-5 3-(3-benzyloxy-phenyl)-benzonitrile 
• 1484-26-0 3-(benzyloxy)aniline 
• 936352-41-9 6-benzyloxy-1-hydroxy-fluoren-9-one 

Relevant articles and documents

ARYL SULFONAMIDES AS SMALL MOLECULE STAT3 INHIBITORS

The present disclosure provides pharmaceutical compositions comprising aryl sulfonamide Stat3 small molecule inhibitors and certain pharmaceutically acceptable salts thereof, and methods of their use for treating cancer.

Preparation method of hydroxyphenylboronic acid

The invention discloses a preparation method of hydroxyphenylboronic acid, which belongs to the technical field of boric acid synthesis in medical intermediates. The method comprises the following steps: starting from bromophenol, carrying out BOC, trimethylsilyl or benzyl protection, forming a Grignard reagent, reacting with borate, or carrying out one-pot reaction with borate and n-butyllithium,and hydrolyzing to obtain hydroxyphenylboronic acid. According to the invention, cheap and easily available protecting groups are adopted, so that the protecting groups are easy to remove during boronation reaction hydrolysis, industrial amplification is easy to realize, batch production is carried out on the scale of dozens of kilograms, and the process stability is good.

METHOD FOR PRODUCING XANTHENE DERIVATIVE, COMPOUND AND SALT THEREOF

PROBLEM TO BE SOLVED: To provide a production method capable of efficiently producing a xanthene derivative at a low cost with fewer production steps compared with conventional production methods in the production of a xanthene derivative, and a compound