531-40-8

Basic information

• Product Name: 2-methoxyphenyl cinnamate
• Synonyms: 2-methoxyphenyl cinnamate;3-Phenylpropenoic acid 2-methoxyphenyl ester;(2-methoxyphenyl) 3-phenylprop-2-enoate;3-phenylacrylic acid (2-methoxyphenyl) ester
• CAS NO: 531-40-8
• Molecular Formula: C₁₆H₁₄O₃
• Molecular Weight: 254.28056
• EINECS: 208-508-6
• Mol File: 531-40-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 413.1°Cat760mmHg
• Flash Point: 175.3°C
• Appearance: /
• Density: 1.156g/cm³
• Vapor Pressure: 4.92E-07mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 2-methoxyphenyl cinnamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxyphenyl cinnamate(531-40-8)
• EPA Substance Registry System: 2-methoxyphenyl cinnamate(531-40-8)

Safety Data

• Hazardous Substances Data: 531-40-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H14O3/c1-18-14-9-5-6-10-15(14)19-16(17)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+

Upstream product

• 102-92-1 cinnamoyl chloride 
• 90-05-1 2-methoxy-phenol 
• 538-56-7 cinnamic acid anhydride 
• 140-10-3 (E)-3-phenylacrylic acid 
• 47589-95-7 boric acid tris-(2-methoxy-phenyl ester) 
• 102-92-1 Cinnamoyl chloride 

Downstream Products

• 54131-15-6 5-hydroxy-6-methoxy-3-phenylindanone 
• 854835-26-0 4'-hydroxy-3'-methoxychalcone 

Relevant articles and documents

Selective synthesis of 3,4-dihydrocoumarins and chalcones from substituted aryl cinnamic esters

Coumarins are ubiquitous in plant kingdom and have been used as antitumor, antifungals, anticoagulants, insecticides. Chalcones are also widespread in plant kingdom and have been known to possess diverse biological activities; antibacterial, antifungal, antitumor and anti-inflammatory, etc. As they are considered as important natural products, numerous synthetic approaches have been reported up to the present. We devise a new selective method of preparing dihydrocoumarins and chalcones from aryl cinnamates by the selection of reagents. Dihydrocoumarin derivatives were prepared selectively by using intramolecular cyclization catalyzed by p-toluene sulfonic acid. Also, chalcones were prepared by Fries-rearrangement catalyzed by TiCl4. This method can be used for preparing various coumarin & chalcone compounds.