5313-35-9Relevant articles and documents
Fluorescent-based solid sensor for HSO4- in water
Tan, Chaoliang,Wang, Qianming,Ma, Lijun
, p. 1191 - 1196 (2010)
In this report, we have shown that the encapsulation of the terbium 2-methylimidazole-4,5-dicarboxylic acid complex into inorganic host tetraethoxysilance is considered to be an efficient way for the design of anion sensors. Strong green emission still can be observed when it disperses in pure water. It was found that the luminescence of hybrid material was selectively turned off rapidly (1 s) by hydrogen sulfate compared with the addition of different anions such as F-, Cl-, Br- and I-. Thin film was successfully prepared and also could be a promising tool for recognizing HSO4-.
Influence of Oxidation Conditions on the Yield of 2-Substituted Imidazole-4,5-dicarboxylic Acids
Brusina,Gubina, Yu. A.,Nikolaev,Ramsh,Piotrovskii
, p. 874 - 878 (2018/07/06)
Conditions were found which allow 2-alkyl-substituted imidazole-4,5-dicarboxylic acids to be synthesized in preparative quantities by the oxidation of 2-alkylbenzimidazoles with hydrogen peroxide. It was shown that optimal results can be obtained at the concentration of 2-alkylimidazole in sulfuric acid of 1 M and the hydrogen peroxide: 2-alkylbenzimidazole molar ratio of 11: 1. Oxidation under these conditions results in higher yields of the target 2-alkylimidazole-4,5-dicarboxylic acids, including those with a branched alkyl group.
JAK-2 MODULATORS AND METHODS OF USE
-
Page/Page column 104-105, (2008/06/13)
This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention