531512-51-3Relevant articles and documents
Solid-phase synthesis of five-dimensional libraries via a tandem Petasis-Ugi multi-component condensation reaction
Portlock, David E.,Naskar, Dinabandhu,West, Laura,Ostaszewski, Ryszard,Chen, Jack J.
, p. 5121 - 5124 (2003)
Five-dimensional libraries of dipeptide amides are readily prepared using a solid-phase tandem Petasis-Ugi multi-component condensation protocol on either a RINK amine or Universal RINK isonitrile resin. The method is practical and can be automated to prepare a large number of compounds useful for high throughput biological screening.