53156-12-0Relevant articles and documents
Octahydrobenzisoquinoline derivatives as antipsychotic agents
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, (2008/06/13)
A class of 1,2,3,4,4a,5,6,10b-octahydrobenz[f]isoquinoline compounds and pharmaceutically acceptable salts of formula I: STR1 wherein, R1 represents hydrocarbon; R2 and R3 independently represent hydrogen, hydrocarbon, halogen, cyano, trifluoromethyl, nitro, --ORx, --SRx, --NRx Ry, --CO2 Rx or together represent methylenedioxy; and Rx and Ry independently represent hydrogen or hydrocarbon. The compounds disclosed herein are selective ligands at sigma recognition sites and are therefore useful in the treatment of psychiatric disorders.