5316-76-7

Basic information

• Product Name: 2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL
• Synonyms: 2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL;2-Amino-5-chloro-4-methyl-1,3-thiazole;2-ThiazolaMine, 5-chloro-4-Methyl-;5-chloro-4-Methylthiazol-2-aMine;5-Chloro-4-methyl-1,3-thiazol-2-amine;5-Chloro-4-methyl-thiazol-2-ylamine;5-chloro-4-methyl-2-Thiazolamine
• CAS NO: 5316-76-7
• Molecular Formula: C₄H₅ClN₂S
• Molecular Weight: 148.61
• Mol File: 5316-76-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 104-108 °C
• Boiling Point: 273°Cat760mmHg
• Flash Point: 118.9°C
• Appearance: /
• Density: 1.447g/cm³
• Vapor Pressure: 0.00587mmHg at 25°C
• Refractive Index: 1.633
• PKA: 4.55±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL(5316-76-7)
• EPA Substance Registry System: 2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL(5316-76-7)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 5316-76-7(Hazardous Substances Data)

Usage

General Description

2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL is a chemical compound that consists of a chlorine atom, a methyl group, and a thiazole ring with an amino group attached to it. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals. 2-AMINO-5-CHLORO-4-METHYLTHIAZOLEHCL is also used in the production of synthetic dyes and pigments. It has several industrial applications, including as a building block in organic synthesis and as a reagent in chemical reactions. Additionally, it has been studied for its potential biological activity, particularly in the field of medicinal chemistry.

InChI:InChI=1/C4H5ClN2S/c1-2-3(5)8-4(6)7-2/h1H3,(H2,6,7)

Upstream product

• 21478-92-2 N-(5-chloro-4-methyl-thiazol-2-yl)-acetamide 
• 6142-15-0 2-amino-4-methylthiazole hydrochloride 
• 513-88-2 1,1-Dichloroacetone 
• 17356-08-0 thiourea 

Downstream Products

• 815608-71-0 N-acetyl-sulfanilic acid-(5-chloro-4-methyl-thiazol-2-ylamide) 

Relevant articles and documents

Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same

Compounds of the formula: STR1 wherein A is S, SO, or SO2, R1 is H or acyl, R2 is H, alkyl, hydroxyalkyl, halogen or carboxy, and R3 is pyridyl are claimed. The compounds are useful as therapeutic agents for the treatment of e.g. rheumatism, nephritis and