53164-08-2 Usage
Description
(5-Methoxy-2-methylindol-3-acetoxy)essigsaeurebenzylester, also known as 5-MeO-MIPT, is a synthetic ester compound that contains a benzyl ester group attached to a molecule of (5-Methoxy-2-methylindol-3-acetoxy)essigsaeure. It is a serotonergic hallucinogen and is known for its psychoactive properties, producing visual and auditory hallucinations, as well as altered perceptions of time and space. This chemical is not approved for medical or recreational use and is classified as a controlled substance in many countries due to its potential for abuse and addiction.
Uses
Used in Research Applications:
(5-Methoxy-2-methylindol-3-acetoxy)essigsaeurebenzylester is used as a research chemical for studying the effects of serotonergic hallucinogens on the human brain and their potential therapeutic applications. It helps researchers understand the mechanisms of action and the risks associated with the use of psychedelic substances.
Used in Controlled Substances Regulation:
(5-Methoxy-2-methylindol-3-acetoxy)essigsaeurebenzylester is used as a reference compound in the development and implementation of regulations and policies related to controlled substances. It aids in the identification and classification of similar compounds to ensure public safety and prevent abuse.
Check Digit Verification of cas no
The CAS Registry Mumber 53164-08-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,1,6 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 53164-08:
(7*5)+(6*3)+(5*1)+(4*6)+(3*4)+(2*0)+(1*8)=102
102 % 10 = 2
So 53164-08-2 is a valid CAS Registry Number.
53164-08-2Relevant articles and documents
Chemical structure and anti-inflammatory activity in the group of substituted indole-3-acetic acids
Boltze,Brendler,Jacobi,Opitz,Raddatz,Seidel,Vollbrecht
, p. 1314 - 1325 (2007/10/02)
The chemical structure of the indometacin molecule was systematically modified with the aim of producing a substance with increased anti-inflammatory activity and improved tolerance. In addition to the variations of the methylene group of the indole-3-acetic acid and substituents on the indole nucleus of indometacin, particular attention was paid to the modification of the carboxyl group of the acetic acid side chain. Among the indometacin esters, one derivative, the [1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetoxy] acetic acid (54), showed an activity approximately twice that of indometacin in the kaolin edema test in the rat paw. Chemical modification of the new compound 54 did not further improve the activity. These studies suggest that specific substitutions on the indole nucleus, in combination with the acetic acid side chain as in 1, and especially the acetoxy acetic acid side chain in 54 are responsible for the high anti-inflammatory activity of this class of substances. Several methods for the synthesis of acemetacin are described.
