53189-75-6Relevant articles and documents
Solvent-free synthesis of monoacylaminals from the reaction of amides and aminals as precursors in carbinolamide synthesis
Sansone, Matthew F.,Koyanagi, Takaoki,Przybyla, David E.,Nagorski, Richard W.
supporting information; experimental part, p. 6031 - 6033 (2010/11/21)
A solvent-free method of generating monoacylaminals by heating the amide and aminal starting materials in the presence of one another has been developed. Yields were generally between 45% and 65% with the monoacylaminal being isolated, needing no further purification after drying under high vacuum.