532-76-3 Usage
Originator
Cyclaine,MSD,US,1952
Uses
Hexylcaine Hydrochloride is used in pain management in as an antifungal agent. Anaesthetic.
Manufacturing Process
A solution of 0.1 mol of 1-cyclohexylamino-2-propanol in 30 grams of
chloroform was saturated with dry hydrogen chloride gas, with cooling. A
solution of 0.1 mol of benzoyl chloride in 30 grams of chloroform was added
and the solution was heated in a bath at 50° to 55°C for four days under a
reflux condenser protected from atmospheric moisture. Then the solvent was
removed by vacuum distillation while the mixture was warmed on a water
bath. Benzene was then added to the syrupy residue and the reaction product
crystallized out after the benzene was removed by vacuum distillation.
The crystallized solid residue was washed with anhydrous ether to remove any
unreacted benzoyl chloride. The 1-cyclohexylamino-2-propyl benzoate
hydrochloride obtained was purified by two recrystallizations from absolute
alcohol. It melted at 177° to 178.5°C.
Therapeutic Function
Local anesthetic
Check Digit Verification of cas no
The CAS Registry Mumber 532-76-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 532-76:
(5*5)+(4*3)+(3*2)+(2*7)+(1*6)=63
63 % 10 = 3
So 532-76-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO2.ClH/c1-13(12-17-15-10-6-3-7-11-15)19-16(18)14-8-4-2-5-9-14;/h2,4-5,8-9,13,15,17H,3,6-7,10-12H2,1H3;1H
