532402-50-9

Basic information

• Product Name: (R)-4-{(E)-2-[(4R,5R)-4,5-Bis-(methoxy-diphenyl-methyl)-[1,3,2]dioxaborolan-2-yl]-vinyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
• Synonyms: (R)-4-{(E)-2-[(4R,5R)-4,5-Bis-(methoxy-diphenyl-methyl)-[1,3,2]dioxaborolan-2-yl]-vinyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
• CAS NO: 532402-50-9
• Molecular Weight: 689.657
• Mol File: 532402-50-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-4-{(E)-2-[(4R,5R)-4,5-Bis-(methoxy-diphenyl-methyl)-[1,3,2]dioxaborolan-2-yl]-vinyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-{(E)-2-[(4R,5R)-4,5-Bis-(methoxy-diphenyl-methyl)-[1,3,2]dioxaborolan-2-yl]-vinyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(532402-50-9)
• EPA Substance Registry System: (R)-4-{(E)-2-[(4R,5R)-4,5-Bis-(methoxy-diphenyl-methyl)-[1,3,2]dioxaborolan-2-yl]-vinyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(532402-50-9)

Safety Data

• Hazardous Substances Data: 532402-50-9(Hazardous Substances Data)

Upstream product

• 130874-89-4 (2R,3R)-1,4-dimethoxy-1,1,4,4-tetraphenyl-2,3-butandiol 
• 162107-48-4 tert-butyl (R)-4-ethynyl-2,2-dimethyloxazolidine-3-carboxylate 

Relevant articles and documents

Synthesis of "Garner" aldehyde-derived cyclopropylboronic esters

The "Garner" aldehyde has been used as a common intermediate for the preparation of the corresponding alkyne 7 and the alkenylboronic esters 12-16 (24-80%). Diastereoselective cyclopropanation afforded cyclopropylboronic esters 17-20 (60-84%, dr 22:78 to 92:8), the configurations of which were determined by chemical correlation (cyclopropanols 22), X-ray structural analysis (of 21a), and characteristic NMR spectroscopic data. The protected amino alcohols 23-26 and amino acids 27 have been synthesised from the cyclopropylboronic esters 19 by oxidation, Matteson homologation or Suzuki coupling. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).