532413-11-9

Basic information

• Product Name: (R)-1,3-Dibenzyl-5-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-dihydro-pyrimidine-2,4-dione
• CAS NO: 532413-11-9
• Molecular Weight: 424.497
• Mol File: 532413-11-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-1,3-Dibenzyl-5-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-dihydro-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1,3-Dibenzyl-5-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-dihydro-pyrimidine-2,4-dione(532413-11-9)
• EPA Substance Registry System: (R)-1,3-Dibenzyl-5-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-dihydro-pyrimidine-2,4-dione(532413-11-9)

Safety Data

• Hazardous Substances Data: 532413-11-9(Hazardous Substances Data)

Upstream product

• 75500-04-8 1,3-dibenzyldihydropyrimidine-2,4(1H,3H)-dione 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 100-39-0 benzyl bromide 

Downstream Products

• 532413-12-0 (R)-1,3-Dibenzyl-5-[(S)-(tert-butyl-dimethyl-silanyloxy)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-dihydro-pyrimidine-2,4-dione 
• 532413-13-1 (S)-1,3-Dibenzyl-5-[(S)-(tert-butyl-dimethyl-silanyloxy)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-dihydro-pyrimidine-2,4-dione 
• 532413-10-8 (S)-1,3-Dibenzyl-5-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-dihydro-pyrimidine-2,4-dione 

Relevant articles and documents

Use of 1,3-dibenzyl-dihydrouracil in the chain extension of 2,3-O-isopropylidene-D-glyceraldehyde

The aldol-type addition of 1,3-dibenzyl-dihydrouracil 2 to 2,3-O-isopropylidene-D-glyceraldehyde 3 was examined in different solvents and under Lewis acid catalysis in order to establish the stereochemical preferences. A stereodivergent synthesis of 5-trihydroxypropyl-dihydrouracil derivatives 4 and its C-5 epimer 5 was realized. The synthesis of ureido polyols 8 and 10 was obtained via the reductive ring opening of the templates 4 and 5.