53257-32-2

Basic information

• Product Name: 4-(BROMOMETHYL)-3,5-DIMETHYLISOXAZOLE
• Synonyms: 4-(BROMOMETHYL)-3,5-DIMETHYLISOXAZOLE
• CAS NO: 53257-32-2
• Molecular Formula: C₆H₈BrNO
• Molecular Weight: 190.03782
• Mol File: 53257-32-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 248.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.490±0.06 g/cm3(Predicted)
• PKA: -1.79±0.28(Predicted)
• CAS DataBase Reference: 4-(BROMOMETHYL)-3,5-DIMETHYLISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(BROMOMETHYL)-3,5-DIMETHYLISOXAZOLE(53257-32-2)
• EPA Substance Registry System: 4-(BROMOMETHYL)-3,5-DIMETHYLISOXAZOLE(53257-32-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 53257-32-2(Hazardous Substances Data)

Upstream product

• 19788-36-4 4-hydroxymethyl-3,5-dimethylisoxazole 

Downstream Products

• 62679-06-5 3,5-Dimethyl-4-methylthiomethylisoxazol 
• 10557-82-1 3,4,5-trimethylisoxazole 
• 75632-85-8 1,2-bis(3,5-dimethylisoxazol-4-yl)ethane 
• 882998-72-3 N-{(E)-3-[1-(3,5-dimethylisoxazol-4-ylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-3,4-difluorobenzenesulfonamide 
• 1076219-63-0 C₃₀H₃₇N₃O₂ 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION

The present disclosure relates generally to compounds and pharmaceutical compositions for the selective inhibition of histone lysine demethylase5 (KDM5), particularly KDM5B, and methods of their use in treating conditions and diseases associated with KDM5 activity.

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.