533923-44-3

Basic information

• Product Name: C₄₉H₆₁F₃N₈O₂₀
• Synonyms: C₄₉H₆₁F₃N₈O₂₀
• CAS NO: 533923-44-3
• Molecular Weight: 1139.06
• Mol File: 533923-44-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₉H₆₁F₃N₈O₂₀(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₉H₆₁F₃N₈O₂₀(533923-44-3)
• EPA Substance Registry System: C₄₉H₆₁F₃N₈O₂₀(533923-44-3)

Safety Data

• Hazardous Substances Data: 533923-44-3(Hazardous Substances Data)

Upstream product

• 17342-08-4 (S)-Pyroglutaminol 
• 533923-42-1 (3S,5S)-5-Azidomethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-oxo-pyrrolidine-1-carboxylic acid benzyl ester 
• 533923-40-9 (S)-2-Azidomethyl-5-oxo-pyrrolidine-1-carboxylic acid benzyl ester 
• 145414-30-8 (+)-(S)-5-(azidomethyl)-2-pyrrolidone 
• 66567-24-6 3,6'-bis-N-benzyloxycarbonylkanamycin A 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 74256-73-8 3,6'-bis(N-benzyloxycarbonyl)-3-N-(trifluoroacetyl)kanamycin A 

Downstream Products

• 533923-46-5 C₄₇H₆₂N₈O₁₉ 

Relevant articles and documents

Probing the functional requirements of the L-haba side-chain of amikacin - Synthesis, 16S A-site rRNA binding, and antibacterial activity

The l-amino group in amikacin was acylated with a variety of 2-hydroxy aminocarboxylic acids to probe the effect of acylation on ribosomal binding and antibacterial activity. The N-hydroxy urea analogue of amikacin (8a) in which the 2-S-hydroxyl-bearing carbon was replaced by an N-OH group was equally active against S. aureus and E. coli in vitro. The analogous tobramycin variant 9 was more active than amikacin.