5344-61-6

Basic information

• Product Name: 1-(2-methoxyphenyl)propan-2-amine
• Synonyms: 1-(2,5-Dichloro-benzenesulfonyl)-1,2,3,4-tetrahydro-quinoline; Quinoline, 1,2,3,4-tetrahydro-1-(2,5-dichlorophenylsulfonyl)-; quinoline, 1-[(2,5-dichlorophenyl)sulfonyl]-1,2,3,4-tetrahydro-
• CAS NO: 5344-61-6
• Molecular Formula: C10H15NO
• Molecular Weight: 0
• Mol File: 5344-61-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 246.7°Cat760mmHg
• Flash Point: 98.1°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 1.02E-09mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 1-(2-methoxyphenyl)propan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methoxyphenyl)propan-2-amine(5344-61-6)
• EPA Substance Registry System: 1-(2-methoxyphenyl)propan-2-amine(5344-61-6)

Safety Data

• Hazardous Substances Data: 5344-61-6(Hazardous Substances Data)

Usage

General Description

The chemical 1-(2-methoxyphenyl)propan-2-amine, also known as 2-Methoxyamphetamine (2-MA), is a psychoactive drug and research chemical that belongs to the amphetamine and phenethylamine classes. It is a synthetic compound with stimulant properties and is known to act as a releasing agent for serotonin, norepinephrine, and dopamine. 2-MA has been made illegal in many countries due to its potential for abuse and adverse health effects. It has been reported to cause symptoms such as agitation, paranoia, and hallucinations, and has been linked to several deaths and serious adverse reactions. The use of 2-MA for recreational purposes is strongly discouraged due to its potential risks and lack of regulated quality and purity.

InChI:InChI=1/C15H13Cl2NO2S/c16-12-7-8-13(17)15(10-12)21(19,20)18-9-3-5-11-4-1-2-6-14(11)18/h1-2,4,6-8,10H,3,5,9H2

Upstream product

• 79-24-3 Nitroethane 
• 135-02-4 ortho-anisaldehyde 
• 5211-62-1 1-(2-methoxyphenyl)propan-2-one 

Relevant articles and documents

Co-Catalyzed Synthesis of Primary Amines via Reductive Amination employing Hydrogen under very mild Conditions

Nanostructured and reusable 3d-metal catalysts that operate with high activity and selectivity in important chemical reactions are highly desirable. Here, a cobalt catalyst was developed for the synthesis of primary amines via reductive amination employing hydrogen as the reducing agent and easy-to-handle ammonia, dissolved in water, as the nitrogen source. The catalyst operates under very mild conditions (1.5 mol% catalyst loading, 50 °C and 10 bar H2 pressure) and outperforms commercially available noble metal catalysts (Pd, Pt, Ru, Rh, Ir). A broad scope and a very good functional group tolerance were observed. The key for the high activity seemed to be the used support: an N-doped amorphous carbon material with small and turbostratically disordered graphitic domains, which is microporous with a bimodal size distribution and with basic NH functionalities in the pores.