53447-08-8 Usage
Description
[18,18,18-2H3]-6-hydroxy-17-methyl-morphinan is a deuterium-labeled chemical compound derived from the naturally occurring alkaloid morphinan, which is found in opium poppy plants. As a synthetic analog of morphinan, it features a hydroxyl group at the 6th position and the incorporation of deuterium, making it valuable for research and potential medical applications.
Uses
Used in Pharmaceutical Research:
[18,18,18-2H3]-6-hydroxy-17-methyl-morphinan is used as a research compound for studying drug metabolism, pharmacokinetics, and other areas of pharmaceutical research. The presence of deuterium in the molecule allows for a better understanding of its behavior in biological systems and can help in the development of new drugs and therapies.
Used in Medical Applications:
In the medical field, [18,18,18-2H3]-6-hydroxy-17-methyl-morphinan may be utilized as a potential therapeutic agent, leveraging its structural similarity to morphinan and the unique properties conferred by the deuterium labeling. This could lead to novel treatments for various conditions, particularly those related to pain management and addiction.
Used in Drug Development:
[18,18,18-2H3]-6-hydroxy-17-methyl-morphinan is used as a starting material or intermediate in the synthesis of other pharmaceutical compounds. Its unique properties, including the presence of deuterium, can be exploited to create new drugs with improved pharmacological profiles, such as enhanced stability, bioavailability, or reduced side effects.
Used in Analytical Chemistry:
This deuterium-labeled compound can be employed as an internal standard or reference material in analytical chemistry, particularly in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. Its use can help improve the accuracy and precision of these analytical techniques, leading to better characterization of related compounds and their interactions with biological targets.
Check Digit Verification of cas no
The CAS Registry Mumber 53447-08-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,4,4 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 53447-08:
(7*5)+(6*3)+(5*4)+(4*4)+(3*7)+(2*0)+(1*8)=118
118 % 10 = 8
So 53447-08-8 is a valid CAS Registry Number.
53447-08-8Relevant articles and documents
Synthesis of [2H3]-dextromethorphan and its major urinary metabolites [2H3]-dextrorphan and [2H3]-dextrorphan-β-glucuronide
Heinkele, Georg,Schaenzle, Gerhard,Muerdter, Thomas E.
, p. 1153 - 1158 (2007/10/03)
Starting from dextromethorphan, [2H3]-dextrorphan-β-glucuronide was synthesized in four steps with [2H3]-dextromethorphan and [2H3]-dextrorphan as intermediates with an overall yield of 11%. Copyright
