53475-49-3

Basic information

• Product Name: 4,6-dimethyl-2-(4-methyl-anilino)-nicotinonitrile
• Synonyms: 4,6-dimethyl-2-(4-methyl-anilino)-nicotinonitrile
• CAS NO: 53475-49-3
• Molecular Weight: 237.304
• Mol File: 53475-49-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,6-dimethyl-2-(4-methyl-anilino)-nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dimethyl-2-(4-methyl-anilino)-nicotinonitrile(53475-49-3)
• EPA Substance Registry System: 4,6-dimethyl-2-(4-methyl-anilino)-nicotinonitrile(53475-49-3)

Safety Data

• Hazardous Substances Data: 53475-49-3(Hazardous Substances Data)

Upstream product

• 14237-71-9 2-chloro-4,6-dimethylnicotinonitrile 
• 106-49-0 p-toluidine 
• 769-28-8 3-Cyano-4,6-dimethyl-2(1H)-pyridon 

Downstream Products

• 82756-23-8 2,4,7-trimethylbenzo[b]-1,8-naphthyridin-5-amine 
• 82756-19-2 2,4,7-Trimethyl-10H-benzo[b][1,8]naphthyridin-5-one 

Relevant articles and documents

Preparation method and application of 5-aminobenzene[b][1,8]naphthyridine compound

The invention belongs to the field of pharmaceutical chemistry, and specifically provides a preparation method and application of a 5-aminobenzene[b][1,8]naphthyridine compound. The preparation methodis a route for synthesis of the 5-aminobenzene [b][1,8] naphthalidine compound by intramolecular cyclization of a molecule of a 4,6-2-disubstituted-2-Naryl-3nitrile compound catalyzed by trifluoro-methanesulfonic acid, more 5-aminobenzene[b][1,8]naphthalidine compounds can be prepared, and the prepared compounds show good antitumor activity in vitro.