5350-82-3

Basic information

• Product Name: 2,2,3-triphenylpropanenitrile
• CAS NO: 5350-82-3
• Molecular Formula: C₂₁H₁₇N
• Molecular Weight: 283.3664
• Mol File: 5350-82-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 400.3°C at 760 mmHg
• Flash Point: 200.4°C
• Density: 1.103g/cm³
• Vapor Pressure: 1.29E-06mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 2,2,3-triphenylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3-triphenylpropanenitrile(5350-82-3)
• EPA Substance Registry System: 2,2,3-triphenylpropanenitrile(5350-82-3)

Safety Data

• Hazardous Substances Data: 5350-82-3(Hazardous Substances Data)

Usage

General Description

2,2,3-triphenylpropanenitrile is a chemical compound with the molecular formula C23H19N. It is a white to off-white solid that is commonly used as a reagent in organic synthesis. It is a versatile compound that can undergo various reactions, such as nucleophilic substitution, addition, and oxidation, making it useful in the production of a wide range of other organic compounds. It is also known for its role as a building block in the synthesis of pharmaceuticals and agrochemicals. Additionally, it has applications in the production of dyes and pigments due to its aromatic properties. Overall, 2,2,3-triphenylpropanenitrile is an important chemical that plays a significant role in the field of organic chemistry.

Upstream product

• 917-64-6 methyl magnesium iodide 
• 86-29-3 Diphenylacetonitrile 
• 174144-11-7 2,2,3-triphenyl-propionic acid amide 
• 100-44-7 benzyl chloride 
• 52826-48-9 N-(Benzyl)-N-(2,2-diphenylethenylidene)amine 
• 18802-83-0 diphenylacetonitrile anion 
• 100-39-0 benzyl bromide 
• 3122-21-2 2,2,3,3-tetraphenylsuccinonitrile 
• 102-04-5 1,3-Diphenylpropanone 
• 40400-13-3 2-Iodobenzyl bromide 
• 4695-13-0 2,2-diphenylacetamide 
• 117-34-0 2,2-diphenylacetic acid 
• 856073-40-0 2,2,3-triphenyl-propionyl chloride 
• 2094-69-1 benzyl pivalate 

Downstream Products

• 58-72-0 Triphenylethylene 
• 2902-61-6 2,2,3-triphenyl-propionic acid 
• 1520-42-9 1,1,2-triphenylethane 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 1416437-67-6 N-phenyl-N-(2,2,3-triphenylpropyl)benzimidamide 
• 1416437-84-7 N-(2,2,3-triphenylpropyl)aniline 
• 703395-54-4 C₂₁H₂₁N 
• 1416437-72-3 1,2,4,5,5-pentaphenyl-1,4,5,6-tetrahydropyrimidine 
• 1424626-72-1 C₃₅H₃₁N₂⁽¹⁺⁾*I^(1-) 
• 1416437-80-3 N¹-methyl-N³,1,2,2-tetraphenylpropane-1,3-diamine 

Relevant articles and documents

Evidence for a Radical Decomposition Mechanism for Diphenyl-N-benzylketene Imine

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Transfer Hydrocyanation of α- and α,β-Substituted Styrenes Catalyzed by Boron Lewis Acids

A straightforward gram-scale preparation of cyclohexa-1,4-diene-based hydrogen cyanide (HCN) surrogates is reported. These are bench-stable but formally release HCN and rearomatize when treated with Lewis acids. For BCl3, the formation of the isocyanide adduct [(CN)BCl3]? and the corresponding Wheland complex was verified by mass spectrometry. In the presence of 1,1-di- and trisubstituted alkenes, transfer of HCN from the surrogate to the C?C double bond occurs, affording highly substituted nitriles with Markovnikov selectivity. The success of this transfer hydrocyanation depends on the Lewis acid employed; catalytic amounts of BCl3 and (C6F5)2BCl are shown to be effective while B(C6F5)3 and BF3?OEt2 are not.

Carbopalladation of nitriles: Synthesis of benzocyclic ketones and cyclopentenones via Pd-catalyzed cyclization of ω-(2-iodoaryl)alkanenitriles and related compounds

An efficient procedure for the synthesis of 2,2-disubstituted benzocyclic ketones by intramolecular carbopalladation of nitriles has been developed. The cyclization of substituted 3-(2-iodoaryl)-propanenitriles affords indanones in high yields. The reaction is compatible with a wide variety of functional groups. This methodology has been extended to the synthesis of tetralones and cyclopentenones.