53527-13-2Relevant articles and documents
STUDIES ON m-CYCLOPHANE FORMATION FROM THE PHOTOLYSIS OF CHLOROACETAMIDE DERIVATIVES
Rezaie, Robert,Bremner, John B.,Blanch, Gregory K.,Skelton, Brian W.,White, Allan H.
, p. 959 - 972 (2007/10/02)
The synthesis of 12-hydroxy-2-oxa-6-azabicyclotrideca-1(13),9,11-trien-5-one (4) is described.Two routes to (4) based on the photolysis of N-chloroacetamide (2b) and N-chloroacetamide (2c) followed by O-demethylation or O-desilylation, were developed.Extension of the work has given the new m-cyclophane ester derivative (9), whose structure has been confirmed by X-ray crystallography.