53546-25-1Relevant articles and documents
Nickel-catalyzed enantioselective alkylative coupling of alkynes and aldehydes: Synthesis of chiral allylic alcohols with tetrasubstituted olefins
Yang, Yun,Zhu, Shou-Fei,Zhou, Chang-Yue,Zhou, Qi-Lin
supporting information; experimental part, p. 14052 - 14053 (2009/03/11)
A highly efficient nickel-catalyzed asymmetric alkylative coupling of alkynes, aldehydes, and dimethylzinc has been realized by using bulky spirobiindane phosphoramidite ligands, affording allylic alcohols with a tetrasubstituted olefin functionality in high yields, high regioselectivities, and excellent enantioselectivities. Copyright