53560-25-1

Basic information

• Product Name: methyl 3-(3,4,5-trimethoxyphenyl)propionate
• Synonyms: methyl 3-(3,4,5-trimethoxyphenyl)propionate
• CAS NO: 53560-25-1
• Molecular Weight: 254.283
• Mol File: 53560-25-1.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: methyl 3-(3,4,5-trimethoxyphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(3,4,5-trimethoxyphenyl)propionate(53560-25-1)
• EPA Substance Registry System: methyl 3-(3,4,5-trimethoxyphenyl)propionate(53560-25-1)

Safety Data

• Hazardous Substances Data: 53560-25-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 66543-72-4 3-(3',4',5'-trimethoxyphenyl)propionyl chloride 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 20069-09-4 piperlongumine 
• 20329-98-0 (E)-3,4,5-trimethoxy-cinnamic acid 
• 25173-72-2 3-(3,4,5-trimethoxyphenyl)propanoic acid 
• 186581-53-3 diazomethane 
• 20329-99-1 (Z)3,4,5-trimethoxycinnamic acid 
• 20329-96-8 methyl 3,4,5-trimethoxycinnamate 
• 2466-36-6 1-(3-(3,4,5-trimethoxyphenyl)propanoyl)piperidin-2-one 
• 7560-49-8 3,4,5-trimethoxycinnamic acid methyl ester 

Downstream Products

• 934749-87-8 3-(2-formyl-3,4,5-trimethoxy-phenyl)-propionic acid methyl ester 
• 93930-23-5 1,2,3-trimethoxy-5-(3-methylbut-2-en-1-yl)benzene 
• 53560-26-2 3-(3,4,5-trimethoxyphenyl)propan-1-ol 
• 1412819-07-8 5-{2-(3,4,5-trimethoxyphenyl)ethyl}-4-(3-methoxyphenyl)-2,4-dihydro-1,2,4-triazole-3-thione 
• 121667-78-5 3-(3',4',5'-trimethoxyphenyl)propanal 
• 182961-38-2 5-(3,4,5-trimethoxyphenyl)pentanoic acid ethyl ester 
• 1403568-93-3 4-(3-methoxyphenyl)-1-(3-(3,4,5-trimethoxyphenyl)propanoyl)thiosemicarbazide 
• 1403569-10-7 C₂₀H₂₃N₃O₄S 
• 1316850-53-9 methyl 3-(3,4,5-trimethoxy-2-(3-methylbut-2-enyl)phenyl)propanoate 
• 1316850-58-4 methyl 3-(3,4,5-trimethoxy-2,6-bis(3-methylbut-2-enyl)phenyl)propanoate 
• 53560-29-5 7,7-Dichlor-3-<3-(3,4,5-trimethoxyphenyl)-propyl>-bicyclo<3.2.0>hepten-(2)-on-(6) 
• 7101-40-8 4-<3-(3,4,5-Trimethoxy-phenyl)-2-propenyl>-tropolon-dihydroverb. 
• 53560-27-3 1-<3-(3,4,5-Trimethoxyphenyl)-propyl>-cyclopentadien 
• 181222-34-4 5-(3-azidopropyl)-1,2,3-trimethoxybenzene 

Relevant articles and documents

Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors

A new series of diaryl heptanones (12a-q) were synthesized and their structures were confirmed by its 1H, 13C NMR and Mass spectral data. These analogs were evaluated for their anti-oxidant activity and potential to inhibit 5-lipoxygenase. Compounds 12k and 12o showed potent in vitro 5-lipoxygenase enzyme inhibitory activity with IC50 values of 22.2, 21.5 μM, which are comparable to curcumin (24.4 μM). Further they also have shown significant antioxidant activity. Molecular docking studies clearly showed correlation between binding energy and potency of these compounds.

Synthesis, acetylcholinesterase and alkaline phosphatase inhibition of some new 1,2,4-triazole and 1,3,4-thiadiazole derivatives

A new series of 4,5-disubstituted-2,4-dihydro-3H-1,2,4-triazole-3-thiones (6as) and 2,5-disubstituted-1,3,4-thiadiazoles (7ah) was synthesized by intramolecular dehydrocyclization of various 1,4-disubstituted thiosemicarbazide derivatives (5as) by refluxing in 4N aqueous sodium hydroxide and by overnight stirring with polyphosphoric acid, respectively. The structures of these compounds were characterized by IR, 1H and 13C NMR, elemental analysis and mass spectroscopic studies. All the synthesized compounds were screened for their acetylcholinesterase and alkaline phosphatase inhibition studies. Most of the tested compounds showed promising activities, amongst them (6k) and (6q) showed excellent acetylcholinesterase inhibitory activity with IC50 0.2410.012 and 0.2600.013M, respectively, as compared with those of standard drug whereas the compound (6p), with IC50 0.0440.001M, was found to be the most potent inhibitor of alkaline phosphatase.

Synthesis of new allocolchicinoids with seven- and eight-membered B-rings by enyne ring-closing metathesis

Total syntheses of allocolchicines 4 and 5, with the ester functionality in the C-ring at the C10 or C11 positions, is reported. An asymmetric synthesis of (7S)-allocolchicine 5 is also described. The main features included the elaboration of a common int