53575-08-9 Usage
Description
DIETHYL 1-NAPHTHYLMETHYLPHOSPHONATE is a clear yellow liquid that serves as an intermediate in the preparation of dual inhibitors for leukocyte proteases, specifically cathepsin G and chymase. These proteases play a significant role in various biological processes and are often associated with inflammatory diseases and immune responses.
Uses
Used in Pharmaceutical Industry:
DIETHYL 1-NAPHTHYLMETHYLPHOSPHONATE is used as an intermediate for the development of dual inhibitors for leukocyte proteases, such as cathepsin G and chymase, for the treatment of various inflammatory diseases and immune disorders. The inhibition of these proteases can help regulate immune responses and alleviate the symptoms of these conditions.
Used in Research and Development:
In the field of research and development, DIETHYL 1-NAPHTHYLMETHYLPHOSPHONATE is utilized as a key compound in the synthesis of novel inhibitors targeting leukocyte proteases. This contributes to the advancement of our understanding of the role of these proteases in disease pathology and the development of potential therapeutic agents.
Used in Drug Design and Synthesis:
DIETHYL 1-NAPHTHYLMETHYLPHOSPHONATE is employed as a building block in the design and synthesis of new drugs that target leukocyte proteases. Its unique chemical properties allow for the creation of innovative drug candidates with potential applications in the treatment of various diseases and conditions related to the immune system and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 53575-08-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,5,7 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 53575-08:
(7*5)+(6*3)+(5*5)+(4*7)+(3*5)+(2*0)+(1*8)=129
129 % 10 = 9
So 53575-08-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H19O3P/c1-3-17-19(16,18-4-2)12-14-10-7-9-13-8-5-6-11-15(13)14/h5-11H,3-4,12H2,1-2H3
53575-08-9Relevant articles and documents
Preparation des acides alkyl et arylalkyl-5 methyl-2 benzofurannedicarboxyliques-6,7. Application a la synthese de derives de nouveaux heterocycles
Cabares, Jacques,Mavoungou-Gomes, Louis
, p. 401 - 412 (2007/10/02)
Direct formation of 5-alkyl or arylalkyl 2-methylbenzofuran 6,7-dicarboxylic acid derivatives from Diels-Alder adducts of 5-alkyl or arylalkyl 2-acetonylfurans and dimethyl acetylenedicarboxylate is promoted by boron trifluoride etherate in methylene chloride at room temperature.The structures of these new compounds were established from their 1H and 13C nmr spectra.In 1,1,2,2-tetrachloroethane and in the presence of aluminium chloride, 5-arylalkylbenzofuran anhydrides undergo an intramolecular Friedel-Crafts acylations leading to new polycyclic benzofuran derivatives.
