53602-19-0Relevant articles and documents
Solvent-free Synthesis and Properties of Functionalized Hydrazines and Bishydrazines as Energetic Ingredients for Propulsion Applications
Eymann, John,Dhenain, Anne,Joucla, Lionel,Jacob, Guy,Lac?te, Emmanuel,Darwich, Chaza
supporting information, p. 4347 - 4357 (2020/11/30)
Functionalized hydrazines and bishydrazines are interesting straightforward precursors for accessing higher nitrogenated compounds. They offer structural diversity and promising energetic properties as well, namely for propulsion applications. A novel and
Reaction of N-alkyl azetidines with triphosgene
Menguy, Laurence,Drouillat, Bruno,Couty, Fran?ois
, p. 6625 - 6628 (2015/11/09)
N-Alkyl azetidines react with triphosgene (BTC) following two possible pathways: N-alkyl ring scission or ring cleavage, to give cyclic or acyclic N-carbamoyl chlorides. Predominance of one pathway over the other is governed by the nature of the substituents on the azetidine ring and on the nitrogen atom as well as by the relative stereochemistry of the ring substituents, and is examined in detail. Some azetidines were identified for their privileged reaction pathway, leading to new functionalized building blocks that were further elaborated into five- or six-membered urea or into azetidinic urea.
PEPTIDYL DERIVATIVES AS METALLOPROTEINASE INHIBITORS
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, (2008/06/13)
Peptidyl derivatives are disclosed that are orally active metalloproteinase inhibitors. The peptidyl derivatives have a selective gelatinase action, have a long duration of action, and are useful in the prophylaxis or treatment of diseases or disorders in which stromelysis, collagenase or gelatinase have a role, for example, in the treatment of cancer to control the development of tumor metastases.