53651-72-2Relevant articles and documents
Modular synthesis of a new family of tripodal ligands, all-cis-1,2,3- tris(diphenyl-phosphinomethyl)cyclopropane and relatives
Schill, Heiko,De Meijere, Armin,Yufit, Dmitry S.
, p. 2617 - 2620 (2007)
Equation Presented Bisbenzyl-protected all-cis-1,2,3-tris(hydroxymethyl) cyclopropane has been obtained in three steps from commercially available cis-2-butene-1,4-diol (75% overall yield) and used to prepare a number of all-1,2,3-trisubstituted cycloprop
Direct Allylation of Active Methylene Compounds with Allylic Alcohols by Use of Palladium/Phosphine-Borane Catalyst System
Shimizu, Aika,Hirata, Goki,Onodera, Gen,Kimura, Masanari
, p. 1954 - 1960 (2018/04/11)
The C?C bond formation between active methylene compounds and allylic alcohols has been newly developed by using a palladium complex as a catalyst together with a phosphine-borane ligand. The best phosphine-borane ligand for this direct allylation has bee
Enantiopure hydroxymethylated cycloalkenols as privileged small molecular multifunctional scaffolds for the asymmetric synthesis of carbocycles
Kumar, Rajan,Rej, Rohan Kalyan,Halder, Joydev,Mandal, Haridas,Nanda, Samik
, p. 498 - 512 (2016/06/06)
Enantiopure hydroxymethylated cycloalkenols bearing a quaternary stereocenter have been synthesized by a Pybox mediated enantioselective desymmetrization method. The synthesized cycloalkenols serve as starting precursors for the construction of several ch
Palladium(II)-Catalyzed Allylic C H Oxidation of Hindered Substrates Featuring Tunable Selectivity Over Extent of Oxidation
Xing, Xiangyou,O'Connor, Nicholas R.,Stoltz, Brian M.
supporting information, p. 11186 - 11190 (2016/07/06)
The use of Oxone and a palladium(II) catalyst enables the efficient allylic C H oxidation of sterically hindered α-quaternary lactams which are unreactive under known conditions for similar transformations. This simple, safe, and effective system for C H activation allows for unusual tunable selectivity between a two-electron oxidation to the allylic acetates and a four-electron oxidation to the corresponding enals, with the dominant product depending on the presence or absence of water. The versatile synthetic utility of both the allylic acetate and enal products accessible through this methodology is also demonstrated.