53658-17-6

Basic information

• Product Name: (2-HYDROXYPHENYL)(ISOXAZOL-4-YL)METHANONE
• Synonyms: 2-(1,2-oxazole-4-carbonyl)phenol
• CAS NO: 53658-17-6
• Molecular Formula: C₁₀H₇NO₃
• Molecular Weight: 189.17
• Mol File: 53658-17-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 333.3°Cat760mmHg
• Flash Point: 155.4°C
• Appearance: /
• Density: 1.332g/cm³
• Vapor Pressure: 7.13E-05mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: (2-HYDROXYPHENYL)(ISOXAZOL-4-YL)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-HYDROXYPHENYL)(ISOXAZOL-4-YL)METHANONE(53658-17-6)
• EPA Substance Registry System: (2-HYDROXYPHENYL)(ISOXAZOL-4-YL)METHANONE(53658-17-6)

Safety Data

• Hazardous Substances Data: 53658-17-6(Hazardous Substances Data)

Usage

General Description

(2-Hydroxyphenyl)(isoxazol-4-yl)methanone is a chemical compound that consists of a phenolic hydroxyl group attached to an isoxazole ring, which is in turn connected to a methanone (carbonyl) group. (2-HYDROXYPHENYL)(ISOXAZOL-4-YL)METHANONE is often used as an intermediate or building block in the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and ability to participate in a variety of chemical reactions. It may also exhibit biological activity and has been studied for potential applications in drug discovery and development. Additionally, its unique structure may make it a valuable tool for research in organic chemistry and medicinal chemistry.

InChI:InChI=1/C10H7NO3/c12-9-4-2-1-3-8(9)10(13)7-5-11-14-6-7/h1-6,12H

Upstream product

• 75825-81-9 4-(o-hydroxybenzoyl)-isoxazole oxime 
• 17422-74-1 3-Formylchromone 
• 61424-75-7 3-formylchromone 3-oxime 

Downstream Products

• 91595-89-0 4-(o-hydroxybenzoyl)-pyrazolone-5 
• 75825-81-9 4-(o-hydroxybenzoyl)-isoxazole oxime 
• 38518-76-2 2-amino-4H-1-benzopyran-4-one 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 

Relevant articles and documents

Reactions of 4-Oxo-4H-1-benzopyran-3-carbaldehyde Oxime Assisted by Lanthanide(III) Cations. Roles of the Ln3+ Size, the Counterion and the Solvent.

The interaction of 4-oxo-4H-1-benzopyran-3-carbaldehyde oxime with some lanthanide(III) salts has been examined by 1H-NMR techniques.While in methanol 4-(2-hydroxybenzoyl)isoxazole is produced, in acetone 2-amino-4-oxo-4H-1-benzopyran-3-carbaldehyde and 4-oxo-4H-1-benzopyran-3-carbonitrile are formed.From the 1H-NMR data, it appears that hbisox is produced via two different pathways, depending on the lanthanide(III) used; Lu(ClO4)3 is about 4 times more reactive than LuCl3, and LaCl3 is completely ineffective, in assisting the hbisox formation; Lu3+ is about 5.5 times more effective than La3+ in assisting the formation of bpa2a and bpn.These differences in reactivity are discussed in terms of the polarizing power of the Ln3+ cation and coordinating ability of the counterion.

BENZO-γ-PYRONES. PART VII. REACTION OF 3-FORMYLCHROMONE WITH HYDROXYLAMINE

-