53666-01-6

Basic information

• Product Name: N-(benzyloxycarbonyl)-L-valine N-hydroxy-5-norbornene-2,3-dicarboximide ester
• Synonyms: N-(benzyloxycarbonyl)-L-valine N-hydroxy-5-norbornene-2,3-dicarboximide ester
• CAS NO: 53666-01-6
• Molecular Weight: 412.442
• Mol File: 53666-01-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(benzyloxycarbonyl)-L-valine N-hydroxy-5-norbornene-2,3-dicarboximide ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzyloxycarbonyl)-L-valine N-hydroxy-5-norbornene-2,3-dicarboximide ester(53666-01-6)
• EPA Substance Registry System: N-(benzyloxycarbonyl)-L-valine N-hydroxy-5-norbornene-2,3-dicarboximide ester(53666-01-6)

Safety Data

• Hazardous Substances Data: 53666-01-6(Hazardous Substances Data)

Upstream product

• 21715-90-2 N-hydroxy-5-norbornene-2,3-dicarboximide 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 137283-63-7 Carbonic acid 3,5-dioxo-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester isopropenyl ester 
• 89028-39-7 N,N'-dinorborneno oxallate(DPO) 

Downstream Products

• 112579-59-6 Z-Val-γAbu-OBzl 
• 77277-62-4 N-(benzyloxycarbonyl)-L-valyl-D-isoglutamine t-butyl ester 
• 73809-01-5 Boc-GlyIleValGlu(OBut)Gln(Mbh)-OH 
• 14485-95-1 Z-IleValGlu(OBut)-OH 
• 5868-49-5 Z-ValGlu(OBut)-OH 
• 57294-39-0 Z-Val-Gly-OBzl 
• 2766-17-8 ethyl N-(benzyloxycarbonyl)-L-valylglycinate 

Relevant articles and documents

An improved method for the synthesis of active esters of N-protected amino acids and subsequent synthesis of dipeptides

4-Dimethylaminopyridine-catalyzed reaction of mixed carbonates 3 with N-protected amino acids 4 gave the corresponding active esters 5-9, from which dipeptides 11-18 were synthesized by aminolysis with amino acids 10.

Syntheses and properties of dipeptides containing gamma-aminobutyric acid or its analogues at the C-terminal.

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The use of N hydroxy 5 norbornene 2,3 dicarboximide active esters in peptide synthesis

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