53684-57-4

Basic information

• Product Name: N-Chlorobetainyl chloride
• Synonyms: N-CHLOROBETAINYL CHLORIDE;2-Chloro-N,N,N-trimethyl-2-oxo-1-ethanaminium chloride;N-Chlorobetainyl chl
• CAS NO: 53684-57-4
• Molecular Formula: C₅H₁₁ClNO*Cl
• Molecular Weight: 172.05
• Product Categories: pharmacetical
• Mol File: 53684-57-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 64 °C
• Appearance: /
• CAS DataBase Reference: N-Chlorobetainyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-Chlorobetainyl chloride(53684-57-4)
• EPA Substance Registry System: N-Chlorobetainyl chloride(53684-57-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 53684-57-4(Hazardous Substances Data)

Usage

General Description

N-Chlorobetainyl chloride is a type of betaine-based surfactant and an important chemical intermediate in organic synthesis. It is primarily used as a reaction reagent in the production of ionic liquids, as well as in the synthesis of various quaternary ammonium compounds. N-Chlorobetainyl chloride is known for its high reactivity as a chlorinating and betainizing agent, making it useful in the pharmaceutical and agrochemical industries for the creation of new compounds with diverse applications. Additionally, it is also a key component of specialty chemicals and plays a crucial role in the development of novel surfactants with unique properties. Despite its reactivity, N-Chlorobetainyl chloride should be handled with care due to its potential corrosive and toxic nature.

InChI:InChI=1/C5H11ClNO.ClH/c1-7(2,3)4-5(6)8;/h4H2,1-3H3;1H/q+1;/p-1

Upstream product

• 590-46-5 acidine 
• 107-43-7 betaine 

Downstream Products

• 3032-11-9 N-<(ethoxycarbonyl)methyl>trimethylammonium chloride 
• 186140-35-2 trimethylammonio-acetic acid-((1R)-menthyl ester); chloride 
• 3032-14-2 Trimethylammoniumessigsaeurebetain-benzylester-chlorid 
• 64308-98-1 cyclohexyloxycarbonylmethyl-trimethyl-ammonium; chloride 
• 136001-24-6 C₆₄H₇₄N₁₂O₄⁽⁴⁺⁾*Cl^(1-) 
• 136001-22-4 tetrakis(4-bentaineamidophenyl)porphyrin 

Relevant articles and documents

Quantifi cation of sterol lipids in plants by quadrupole time-of-fl ight mass spectrometry

Glycerolipids, sphingolipids, and sterol lipids constitute the major lipid classes in plants. Sterol lipids are composed of free and conjugated sterols, i.e., sterol esters, sterol glycosides, and acylated sterol glycosides. Sterol lipids play crucial roles during adaption to abiotic stresses and plant - pathogen interactions. Presently, no comprehensive method for sterol lipid quantifi cation in plants is available. We Q1 used nanospray ionization quadrupole-time-of-fl ight mass spectrometry (Q-TOF MS) to resolve and identify the molecular species of all four sterol lipid classes from Arabidopsis thaliana . Free sterols were derivatized with chlorobetainyl chloride. Sterol esters, sterol glycosides, and acylated sterol glycosides were ionized as ammonium adducts. Quantifi cation of molecular species was achieved in the positive mode after fragmentation in the presence of internal standards. The amounts of sterol lipids quantifi ed by Q-TOF MS/MS were validated by comparison with results obtained with TLC/GC. Quantifi cation of sterol lipids from leaves and roots of phosphate-deprived A. thaliana plants revealed changes in the amounts and molecular species composition. The Q-TOF method is far more sensitive than GC or HPLC. Therefore, Q-TOF MS/MS provides a comprehensive strategy for sterol lipid quantifi cation that can be adapted to other tandem mass spectrometers. Copyright

Transmembrane ion channels constructed of cholic acid derivatives

A new class of supramolecular transmembrane ion channels was prepared by linking two amphiphilic cholic acid methyl ethers through biscarbamate bonds to afford bis(7,12-dimethyl-24-carboxy-3-cholanyl)-N,N′-xylylene dicarbamate 2 and bis[7,12-dimethyl-24-(N,N,N-trimethylethanaminium-2-carboxylate) -3-cholanyl]-N,N′-xylylene dicarbamate dichloride 3. When incorporated into a planar bilayer membrane, both compounds showed stable (lasting 10 ms to 10 s) single ion channel currents. Only limited numbers of relatively small conductances were characterized for these channels (5-20 pS for 2 and 5-10 pS for 3, 10 and 17 pS for 2, and 9 pS for 3 in particular). Both channels were cation selective, and permeability ratios of potassium cation to chloride anion were 17 and 7.9 for 2 and 3, respectively, reflecting the difference in ionic species of the headgroup. Both channels 2 and 3 showed significant potassium selectivity over sodium by a factor of 3.1 and 3.2, respectively. No Li+ currents were observed for 2, showing sharp discrimination between Na+ or K+.

A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS

The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.

NEW BIS ESTERS OF IVY SAPOGENINS FOR RUMINANTS

The present invention relates to synthetic bis esters of hederagenin, and their use in ruminants to improve ruminant growth performance, reduce rumen methane emission, reduce urine ammonia excretion, and/or to reduce rumen acetate to propionate ratio. Moreover, it also relates to a feed composition for ruminants comprising bis esters of hederagenin, and to novel bis esters of hederagenin.