5370-33-2Relevant articles and documents
A New Carbanionic One-Carbon Ring Enlargement-Alkylation of Lactams
Valacchi, Michela,Cabri, Walter,Mordini, Alessandro,De Philippis, Arnault,Reginato, Gianna
, p. 2025 - 2028 (2003)
The lithium-bromine exchange of bicyclic bromo-substituted γ- and δ-lactams has been investigated finding that the lithium intermediates undergo a ring-enlargement reaction eventually leading to the isomeric six- and seven-membered lactams. Interception of the lithium species with electrophiles allows the synthesis of a series of functionalized quinolinones and benzoazepines.
PHOTOCYCLIZATION OF ENAMIDES. 38 REDUCTIVE PHOTOCYCLIZATION OF α-(METHYLTHIO)- AND α-(ARYLTHIO)ENAMIDES
Naito, Takeaki,Tanada, Hiromi,Suzuki, Yumiko,Saito, Haruko,Kiguchi, Toshiko,Ninomiya, Ichiya
, p. 2345 - 2366 (2007/10/02)
Reductive photocyclization of α-(methylthio)enamide (2) gave exclusively six-membered lactams (3) and (4) while the same reaction of α-(arylthio)enamides (6) and (12) was found to afford five-membered lactams (7) and (13) as major products.A novel total s