53703-96-1

Basic information

• Product Name: 1-benzyl-6-chloro-2-phenyl-1H-benzo[d]imidazole
• Synonyms: 1-benzyl-6-chloro-2-phenyl-1H-benzo[d]imidazole
• CAS NO: 53703-96-1
• Molecular Weight: 318.805
• Mol File: 53703-96-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-benzyl-6-chloro-2-phenyl-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-6-chloro-2-phenyl-1H-benzo[d]imidazole(53703-96-1)
• EPA Substance Registry System: 1-benzyl-6-chloro-2-phenyl-1H-benzo[d]imidazole(53703-96-1)

Safety Data

• Hazardous Substances Data: 53703-96-1(Hazardous Substances Data)

Upstream product

• 1402938-87-7 (Z)-N-(2-bromo-4-chlorophenyl)benzimidoyl chloride 
• 100-46-9 benzylamine 
• 98-88-4 benzoyl chloride 
• 873-38-1 4-chloro-2-bromoaniline 
• 956-29-6 N-(2-bromo-4-chlorophenyl)benzamide 
• 53703-81-4 N¹,N²-dibenzyl-4-chlorobenzene-1,2-diamine 
• 100-44-7 benzyl chloride 
• 95-83-0 4-Chloro-1,2-phenylenediamine 
• 100-51-6 benzyl alcohol 
• 55-21-0 benzamide 
• 823-57-4 2-bromo-5-chloroaniline 
• 100-39-0 benzyl bromide 
• 2866-82-2 N-(4-chlorophenyl)benzamide 
• 93-98-1 N-phenyl benzoyl amide 

Relevant articles and documents

Preparation method of benzimidazole compounds in sterilizing agent and pesticide

The invention provides a new synthesis method of benzimidazole compounds which can be applied to preparation of disinfectants and pesticides, and the benzimidazole compounds are synthesized by using oxalyl diamine compounds which are simple and easy to prepare as ligands and using CuI to catalyze o-amide substituted chlorinated aryl compounds. The method has the advantages that a reaction system is cheap and easy to prepare, the method can be suitable for industrial production, and reaction conditions are mild. In addition, the reaction also has the advantages of low catalyst and ligand equivalents, simplicity, convenience, economy, wide substrate application range and the like. The benzimidazole compound obtained by the preparation method can be used as a killing agent and a pesticide bactericide.

Nickel-catalysed dehydrogenative coupling of aromatic diamines with alcohols: Selective synthesis of substituted benzimidazoles and quinoxalines

The first nickel-catalysed dehydrogenative coupling of primary alcohols and ethylene glycol with aromatic diamines for selective synthesis of mono- and di-substituted benzimidazoles and quinoxalines is reported. The earth-abundant, non-precious and simple NiCl2/L1 system enables the synthesis of N-heterocycles releasing water and hydrogen gas as byproducts. Mechanistic studies involving deuterium labeling experiments and quantitative determination of hydrogen gas evaluation were performed.

Solvent/oxidant-switchable synthesis of multisubstituted quinazolines and benzimidazoles via metal-free selective oxidative annulation of arylamidines

A fast and simple divergent synthesis of multisubstituted quinazolines and benzimidazoles was developed from readily available amidines, via iodine(III)-promoted oxidative C(sp3)-C(sp2) and C(sp 2)-N bond formation in nonpolar and polar solvents, respectively. Further selective synthesis of quinazolines in polar solvent was realized by TEMPO-catalyzed sp3C-H/sp2C-H direct coupling of the amidine with K2S2O8 as the oxidant. No metal, base, or other additives were needed.