53753-58-5

Basic information

• Product Name: Phosphine oxide, bis(1-methylethyl)-
• Synonyms: Diisopropylphosphinigsaeure;2-(propan-2-ylphosphonoyl)propane;Diisopropylphosphinsaeure;diisopropylphosphine Oxide;Diisopropylphosphinoxid;Phosphine oxide,bis(1-methylethyl);diisopropylphosphinic acid
• CAS NO: 53753-58-5
• Molecular Formula: C6H15OP
• Molecular Weight: 134.158
• Mol File: 53753-58-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, bis(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, bis(1-methylethyl)-(53753-58-5)
• EPA Substance Registry System: Phosphine oxide, bis(1-methylethyl)-(53753-58-5)

Safety Data

• Hazardous Substances Data: 53753-58-5(Hazardous Substances Data)

Upstream product

• 948311-76-0 [2,6-(ⁱPr₂PO)₂C₆H₃]NiCl 

Downstream Products

• 74756-83-5 C₁₆H₂₈O₂P₂ 
• 74756-90-4 C₁₆H₂₈O₂P₂ 
• 58393-52-5 diisopropyl((p-methylphenyl)sulfanyl)phosphonate 
• 538-86-3 benzyl methyl ether 
• 20491-53-6 di-isopropylphosphine 
• 34887-74-6 1-Phenylaethyl-Diisopropylphosphinat 
• 96199-75-6 <α-Hydroxy-benzyl>-diisopropyl-phosphinoxid 

Relevant articles and documents

Study of the Reactivity of the [(PE1CE2P)Ni(II)] (E1, E2 = O, S) Pincer System with Acetonitrile and Base: Formation of Cyanomethyl and Amidocrotononitrile Complexes versus Ligand Decomposition by P-S Bond Activation

Nickel(II) chloride complexes with PE1CE2P (E = O, S) pincer ligands were used as precursors for the generation of cyanomethyl complexes in order to investigate the influence of variations (O vs S) in the side arms of the ligands on reactivity and stability of such compounds. In this regard, five hitherto unknown Ni(II) compounds were synthesized and fully characterized. Reaction of the Ni(II) chloride complex [(iPrPOCSPiPr)NiCl] (2-Cl) with 1 equiv of base and nitrile furnishes the cyanomethyl complex [(iPrPOCSPiPr)NiCH2CN] (2-CM). Increase of the amount of base and nitrile results in the formation of 3-amidocrotononitrile complexes [(iPrPOCOPiPr)NiNHC(CH3)CHCN] (1-ACN) and [(iPrPOCSPiPr)NiNHC(CH3)CHCN] (2-ACN). In contrast, similar reactions of the bis(thiophosphinite) complex 3-Cl resulted in formation of a tetranuclear Ni cluster (4) or a dinuclear 1,3-dithiolate-bridged PSCSP complex 5 by unexpected cleavage of P-S bonds of the pincer ligand.