53783-90-7Relevant articles and documents
A formal total synthesis of (±)-ferruginine by Pd-catalyzed intramolecular aminocarbonylation
Ham, Won-Hun,Jung, Young Boon,Lee, Kyunghae,Oh, Chang-Young,Lee, Kee-Young
, p. 3247 - 3248 (1997)
A practical and efficient synthetic route to the neuroactive alkaloid ferruginine has been developed. 8-Azabicyclo[3.2.1]octane skeleton 4 was prepared in one step by intramolecular aminocarbonylation of 3 catalyzed by palladium.
PLEUROMUTILIN DERIVATIVES FOR USE IN THE TREATMENT OF DISEASES MEDIATED BY MICROBES
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, (2014/12/12)
Compounds selected from the group of N-unsubstituted or N-alkylated or N-acylated 14-O-[(amino(C0-4)alkyl-hydroxy-cycloalkyl- or bicycloalkylsulfanyl)-acetyl]-mutilins which are 14-O-[(amino(C0-4)alkyl-hydroxy-cyclobutylsulfanyl)-acetyl]-mutilins, 14-O-[(amino(C0-4)alkyl-hydroxy-cyclopentylsulfanyl)-acetyl]-mutilins, 14-O-[(amino(C0-4)alkyl-hydroxy- cycloheptylsulfanyl)-acetyl]-mutilins, 14-O-[(amino(C0-4)alkyl-hydroxy-cyclooctylsulfanyl)- acetyl]-mutilins, or 14-O-[(amino(C0-4)alkyl-hydroxy-bicycloalkylsulfanyl)-acetyl]-mutilins, optionally in the form of a salt and/or a solvate, a pharmaceutical compositions comprising such compounds and their use as pharmaceuticals, e.g. for the treatment of microbial infections and for the treatment of acne, optionally in combination with other pharmaceutically active agents.