53790-13-9

Basic information

• Product Name: 5,10,15,20,22,24-Hexahydrouroporphyrin II
• Synonyms: 5,10,15,20,22,24-Hexahydrouroporphyrin II;Uroporphyrinogen II
• CAS NO: 53790-13-9
• Molecular Formula: C40H44N4O16
• Molecular Weight: 836.79456
• Mol File: 53790-13-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,10,15,20,22,24-Hexahydrouroporphyrin II(CAS DataBase Reference)
• NIST Chemistry Reference: 5,10,15,20,22,24-Hexahydrouroporphyrin II(53790-13-9)
• EPA Substance Registry System: 5,10,15,20,22,24-Hexahydrouroporphyrin II(53790-13-9)

Safety Data

• Hazardous Substances Data: 53790-13-9(Hazardous Substances Data)

Upstream product

• 75993-21-4 3-(5-[5-Aminomethyl-4-(2-carboxy-ethyl)-3-carboxymethyl-1H-pyrrol-2-ylmethyl]-2-{3-(2-carboxy-ethyl)-5-[4-(2-carboxy-ethyl)-3-carboxymethyl-1H-pyrrol-2-ylmethyl]-4-carboxymethyl-1H-pyrrol-2-ylmethyl}-4-carboxymethyl-1H-pyrrol-3-yl)-propionic acid 
• 75993-22-5 4-<2-(methoxycarbonyl)ethyl>-3-<(methoxycarbonyl)methyl>pyrrole-5-carboxylic acid 
• 75975-52-9 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 72423-67-7 benzyl 2-iodo-3<(methoxycarbonyl)methyl>-4-<β-(methoxycarbonyl)ethyl>-5-pyrrolecarboxylate 
• 72423-57-5 5-benzyloxycarbonyl-4-(2-methoxycarbonylethyl)-3methoxycarbonylmethylpyrrole-2-carboxylic acid 
• 75975-55-2 tert-butyl 3,3'-bis<(methoxycarbonyl)methyl>-4,4'-bis<β-(methoxycarbonyl)ethyl>dipyrrylmethane-5-carboxylate 
• 75993-23-6 tert-butyl 3,3'-bis<(methoxycarbonyl)methyl>-4,4'-bis<β-(methoxycarbonyl)ethyl>-5'-carboxydipyrrylmethane-5-carboxylate 
• 75975-54-1 tert-butyl 3,3'-bis<(methoxycarbonyl)methyl>-4,4'-bis<β-(methoxycarbonyl)ethyl>-5-<(benzyloxy)carbonyl>dipyrrylmethane-5-carboxylate 
• 75975-61-0 1,4,5-tris<β-(methoxycarbonyl)ethyl>-2,3,6,7-tetrakis<(methoxycarbonyl)methyl>-8-(β-carboxyethyl)-8'-(aminomethyl)bilane lactam 
• 50622-60-1 3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-pyrrole-2-carboxylic acid benzyl ester 
• 50622-64-5 benzyl 3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethyl-5-methylpyrrole-2-carboxylate 
• 75975-56-3 tert-butyl 3,3'-bis<(methoxycarbonyl)methyl>-4,4'-bis<β-(methoxycarbonyl)ethyl>-5'-formyldipyrrylmethane-5-carboxylate 

Relevant articles and documents

Synthesis of substrate analogs of methyltransferases in the vitamin B12 biosynthetic pathway and characterization of their enzymatic products

The specificity toward substrate analogs of the first two methyltransferases in the vitamin B12 biosynthetic pathway was probed with 15 synthetic porphyrinogens. Several novel methylated chlorins and isobacteriochlorins were isolated and charac

Biosynthesis of Porphyrins and Related Macrocycles. Part 15. Chemical and Enzymic Formation of Uroporphyrinogen Isomers from Unrearranged Aminomethylpyrromethane: Separation of Isomeric Coproporphyrin Esters

The unrearranged pyrromethane (1) is transformed chemically mainly into uro'gen-I with a smaller amount of uro'gen-IV but only traces of uro'gen-III are formed.Uro'gen-I is produced via a tetrapyrrolic (bilane) intermediate and when the diaminase-cosynthetase enzyme system from Euglena gracilis is present, this intermediate is converted into uro'gen-III.The rearrangement step for this conversion has the same characteristics found earlier for the natural biosynthetic process from porphobilinogen.Pyrromethane (1) is not a direct biosynthetic precursor of uro'gen-III and reasons are advanced why this is understandable.Methods are developed based on high pressure liquid chromatography for the separation of all four isomeric coproporphyrin esters.