53911-68-5

Basic information

• Product Name: BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE
• Synonyms: B-(4-CHLOROPHENYL) GLUTARIC ANHYDRIDE;BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE;3-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE;4-(4-CHLORO-PHENYL)-DIHYDRO-PYRAN-2,6-DIONE;4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione; 3-(p-Chlorophenyl)glutaric Anhydrid;3-(4-CHLOROPHENYL)GLUTARIC ACID ANHYDRIDE;3-(p-Chlorophenyl)glutaric Anhydride
• CAS NO: 53911-68-5
• Molecular Formula: C₁₁H₉ClO₃
• Molecular Weight: 224.64
• EINECS: 258-858-9
• Product Categories: Heterocyclic Compounds;Aromatics Compounds;Aromatics;Heterocycles
• Mol File: 53911-68-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 393.2 °C at 760 mmHg
• Flash Point: 176 °C
• Appearance: white solid
• Density: 1.348 g/cm³
• Refractive Index: 1.594
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE(53911-68-5)
• EPA Substance Registry System: BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE(53911-68-5)

Safety Data

• Hazardous Substances Data: 53911-68-5(Hazardous Substances Data)

Usage

Description

BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE, also known as 3-(4-Chlorophenyl)glutaric Anhydride, is an organic compound with the CAS number 53911-68-5. It is a white solid and is primarily used in the field of organic synthesis due to its unique chemical properties.

Uses

Used in Organic Synthesis:
BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE is used as a synthetic intermediate for the production of various pharmaceuticals and chemicals. Its chemical structure allows it to be a versatile building block in the synthesis of complex molecules, contributing to the development of new drugs and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE is used as a key component in the development of new drugs. Its unique properties enable it to be incorporated into the molecular structure of potential therapeutic agents, enhancing their efficacy and selectivity.
Used in Chemical Industry:
BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE is also utilized in the chemical industry for the production of various chemicals and materials. Its reactivity and structural features make it a valuable compound for the synthesis of specialty chemicals, additives, and other industrial products.

InChI:InChI=1/C22H20Cl2O7/c23-17-5-1-13(2-6-17)15(9-19(25)26)11-21(29)31-22(30)12-16(10-20(27)28)14-3-7-18(24)8-4-14/h1-8,15-16H,9-12H2,(H,25,26)(H,27,28)

Upstream product

• 35271-74-0 3-(4-chlorophenyl)pentane-1,5-dioic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 101104-10-3 diethyl 3-(4-chlorophenyl)glutarate 
• 463-51-4 Ketene 
• 1158997-06-8 C₉H₇ClO₂ 
• 108-24-7 acetic anhydride 
• 84803-73-6 C₁₉H₂₃ClO₆ 

Downstream Products

• 108369-65-9 3-(4-chloro-phenyl)-5-(2,4-dimethoxy-phenyl)-5-oxo-valeric acid 
• 5045-65-8 3-(4-chlorophenyl)-glutaric acid monomethyl ester 
• 94760-33-5 3-(4-Chloro-phenyl)-4-[2-(3,4-dimethoxy-phenyl)-ethylcarbamoyl]-butyric acid 
• 348110-33-8 5-[N'-(9H-fluoren-9-ylmethoxycarbonyl)-hydrazino]-5-oxo-3-(4-chloro)-phenylpentanoic acid 
• 860011-99-0 3-(4-chlorophenyl)-glutaric acid monoethyl ester 
• 860012-01-7 (S)-3-(4-chlorophenyl)-glutaric acid monoethyl ester 
• 183504-76-9 (R)-3-(4-chlorophenyl)-glutaric acid monoethyl ester 
• 137310-16-8 (R)-3-(4-chlorophenyl)-glutaric acid monomethyl ester 
• 865366-99-0 (S)-3-(4-chlorophenyl)-glutaric acid monomethyl ester 
• 865367-02-8 (S)-3-(4-chlorophenyl)-glutaric acid monoallyl ester 
• 865367-01-7 (S)-3-(4-chloro-phenyl)pentanedioic acid monobenzyl ester 
• 865367-00-6 (S)-3-(4-chlorophenyl)-glutaric acid monobutyl ester 
• 722549-40-8 ethyl 6-chloro-3-(4-chlorophenyl)-5-oxohexanoate 
• 761401-08-5 3-(4-chloro-phenyl)-4-{2-[3-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-propyl]-thiazol-4-yl}-butyric acid ethyl ester 

Relevant articles and documents

Glycinamide derivative as well as preparation method and application thereof

The invention discloses a glycinamide derivative as well as a preparation method and application thereof. The derivative with a structural formula as shown in the following formula (I) is provided; and in the formula, R1 is selected from Cl and H, R2 is one selected from H, CH3 and CH2CH3; and X is one selected from NHCH3, NHCH2CH3, N (CH2CH3) 2, a pyrrolyl group and a piperidyl group. During preparation, different phenyl glutaric acid compounds are selected as raw materials and are respectively subjected to amidation reaction twice with an aminoindane hydrochloride derivative and an ethylenediamine derivative to obtain a target derivative. The prepared derivative or the pharmaceutically acceptable salt thereof, or the pharmaceutical composition thereof can be used as an S-adenosyl homocysteine hydrolase inhibitor for the development of antitumor drugs .

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.