53940-02-6

Basic information

• Product Name: 2-Propen-1-one, 3-phenyl-1-(3-pyridinyl)-, (2E)-
• CAS NO: 53940-02-6
• Molecular Formula: C14H11NO
• Molecular Weight: 209.247
• Mol File: 53940-02-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-phenyl-1-(3-pyridinyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-phenyl-1-(3-pyridinyl)-, (2E)-(53940-02-6)
• EPA Substance Registry System: 2-Propen-1-one, 3-phenyl-1-(3-pyridinyl)-, (2E)-(53940-02-6)

Safety Data

• Hazardous Substances Data: 53940-02-6(Hazardous Substances Data)

Upstream product

• 350-03-8 methyl-3-pyridylketone 
• 103-49-1 dibenzylamine 
• 86535-76-4 3-phenyl-1-(pyridin-3-yl)prop-2-yn-1-one 
• 500-22-1 3-pyridinecarboxaldehyde 
• 103-63-9 1-phenyl-2-bromoethane 
• 264625-65-2 3-(azidomethyl)-2-phenylpyridine 
• 102-92-1 Cinnamoyl chloride 
• 56-23-5 tetrachloromethane 
• 7732-18-5 water 
• 100-52-7 benzaldehyde 

Downstream Products

• 101280-54-0 4-nitro-3-phenyl-1-[3]pyridyl-pentan-1-one 
• 101575-07-9 4-nitro-3-phenyl-1-[3]pyridyl-hexan-1-one 
• 115604-81-4 4-nitro-3,5-diphenyl-1,7-di-[3]pyridyl-heptane-1,7-dione 
• 103036-22-2 3-fluoren-9-yl-3-phenyl-1-[3]pyridyl-propan-1-one 
• 116281-46-0 2-(fluoren-9-yl-phenyl-methyl)-3-phenyl-1,5-di-[3]pyridyl-pentane-1,5-dione 
• 33391-85-4 3-morpholin-4-yl-3-phenyl-1-pyridin-3-yl-propan-1-one 
• 101890-83-9 (3-oxo-1-phenyl-3-[3]pyridyl-propyl)-malonic acid dimethyl ester 
• 27046-76-0 3-(1,5-diphenyl-4,5-dihydro-1H-pyrazol-3-yl)-pyridine 
• 103329-08-4 9-(3-oxo-1-phenyl-3-[3]pyridyl-propyl)-fluorene-9-carboxylic acid ethyl ester 
• 20915-54-2 4-methyl-4-nitro-3-phenyl-1-[3]pyridyl-pentan-1-one 

Relevant articles and documents

Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines

The structure of alpha-napthoflavone (ANF), a potent inhibitor of CYP1A1 and CYP1B1, mimics the structure of chalcones. Two potent CYP1B1 inhibitors 7k (DMU2105) and 6j (DMU2139) have been identified from two series of synthetic pyridylchalcones. They inh

Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

Metal-free synthesis of chalcone derivatives through a tandem cross-dehydrogenative-coupling/elimination reaction is described. A simple and inexpensive ammonium persulfate salt enables the reaction between ketones and benzylamines to proceed with high stereoselectivity and good functional group compatibility.

Stereoselective reduction of 1-acyl-2-phenylacetylenes with triphenylphosphine in water: An efficient synthesis of E-chalcones

1-Acyl-2-phenylacetylenes are reduced with triphenylphosphine in water under mild conditions (room temperature, without catalyst and organic solvent, 3 h) to afford (E)-1-acyl-2- phenylethenes (chalcones) in high yields (83-91%). ARKAT-USA, Inc.