53949-13-6

Basic information

• Product Name: 4-(2-methylbenzylidene)-2-phenyloxazol-5-one
• CAS NO: 53949-13-6
• Molecular Weight: 263.296
• Mol File: 53949-13-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 4-(2-methylbenzylidene)-2-phenyloxazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-methylbenzylidene)-2-phenyloxazol-5-one(53949-13-6)
• EPA Substance Registry System: 4-(2-methylbenzylidene)-2-phenyloxazol-5-one(53949-13-6)

Safety Data

• Hazardous Substances Data: 53949-13-6(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 529-20-4 2-methylphenyl aldehyde 
• 42013-20-7 2-[(2-methylphenyl)formamido]acetic acid 
• 100-52-7 benzaldehyde 
• 98-88-4 benzoyl chloride 
• 108-24-7 acetic anhydride 
• 1199-01-5 2-phenylazlactone 

Downstream Products

• 1323141-12-3 C₂₂H₂₄N₂O₂ 
• 1323140-59-5 (Z)-N-(1-chloro-3-oxo-3-(piperidin-1-yl)-1-o-tolylprop-1-en-2-yl)benzamide 
• 1328630-17-6 [Pd2(2-phenyl-4-(6-methylbenzylidene-κC2)-(4H)-1,3-oxazol-5-one(1-))2(μ-trifluoroacetato)2] 
• 1562376-83-3 (3R,3aS,9bR)-diethyl 3a-benzamido-4-oxo-3-(o-tolyl)-1,3a,4,9b-tetrahydrochromeno[4,3-b]pyrrole-2,2(3H)-dicarboxylate 
• 72615-62-4 (Z)-2-Benzoylamino-3-o-tolyl-acrylic acid 
• 72615-48-6 (Z)-2-Benzoylamino-3-o-tolyl-acrylic acid methyl ester 
• 95320-52-8 4-(2-methyl-benzhydryl)-2-phenyl-4H-oxazol-5-one 

Relevant articles and documents

Chemoselective Transfer Hydrogenation of Enamides Using Ru Pincer Complexes for the Synthesis of α-Amino Acids

The chemoselective reduction of enamides to α-amino acids with iPrOH and EtOH as H-donors and solvents catalyzed by Ru pincer complexes is demonstrated. A range of α-amino acids is synthesized in good to excellent yields. Applications, large scale, and a one-pot experiment are also reported. Finally, deuterium-labeling experiments show high regioselectivity between the α-and β-positions of the alkene unit.

Enantioselective [4 + 2]-Annulation of Azlactones with Copper-Allenylidenes under Cooperative Catalysis: Synthesis of α-Quaternary α-Acylaminoamides

The first enantioselective decarboxylative [4 + 2]-annulation of ethynyl benzoxazinanones with azlactones has been developed under cooperative copper and bifunctional tertiary aminourea catalysis. This direct and modular approach combines dipolar copper-a

Synthesis and insecticidal evaluation of tetrahydroimidazo[1,2-a]pyridin-5(1H)-one derivatives

A series of novel tetrahydroimidazo[1,2-a]pyridine-5(1H)-one derivatives containing a electronegative pharmacophore (=CNO2) were synthesized via practical aza-ene reaction and characterized by 1H NMR, 13C NMR, 19F NMR and HRMS. Preliminary bioassays showed that some of the target compounds exhibited good insecticidal activity against brown planthopper (Nilaparvata lugens) and cowpea aphids (Aphis craccivora) at 500 mg L-1. Among them, compound 11h was active against brown planthopper at 100 mg L-1. The insecticidal activities varied significantly depending on the types and patterns of the substituents, which provided guidance for further investigation on structure modifications.