53951-34-1

Basic information

• Product Name: Benzene, 1-(dibutoxymethyl)-2-nitro-
• CAS NO: 53951-34-1
• Molecular Formula: C15H23NO4
• Molecular Weight: 281.352
• Mol File: 53951-34-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(dibutoxymethyl)-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(dibutoxymethyl)-2-nitro-(53951-34-1)
• EPA Substance Registry System: Benzene, 1-(dibutoxymethyl)-2-nitro-(53951-34-1)

Safety Data

• Hazardous Substances Data: 53951-34-1(Hazardous Substances Data)

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 71-36-3 butan-1-ol 

Downstream Products

• 1074-88-0 1H-indole-7-carbaldehyde 
• 167479-16-5 1-methylindolyl-7-carboxylic acid 

Relevant articles and documents

Piperidine compound and preparation method and medical application thereof

The invention discloses a piperidine compound shown as a formula (I) and a preparation method and medical application thereof, and particularly relates to a piperidine USP7 inhibitor compound or pharmaceutically acceptable salt or ester or solvate thereof and a preparation method and application of the piperidine USP7 inhibitor compound or pharmaceutically acceptable salt or ester or solvate thereof. The compound provided by the invention can inhibit the activity of USP7 enzyme, has very good selectivity and druggability, and can be used for preparing medicines for preventing or treating tumor diseases or virus infectious diseases.

A rhodium(ii) catalysed domino synthesis of azepino fused diindoles from isatin tethered: N -sulfonyl-1,2,3-triazoles and indoles

An efficient and convenient protocol for the synthesis of a novel class of azepino fused diindoles from isatin tethered N-sulfonyl-1,2,3-triazoles and indoles has been disclosed. The reaction proceeds via denitrogenative aza-vinyl rhodium carbene formation to give a carbonyl ylide, which with indole results in 1,3-dipolar cycloaddition followed by sequential semipinacol rearrangement/ring expansion/oxidation to produce azepino fused diindoles. The reaction shows a broad substrate scope giving up to 81% yield. Furthermore, reversible catalytic hydrogenation and photophysical studies were carried out to demonstrate the application of these molecules.

Aminocatalyzed Cascade Synthesis of Enantioenriched 1,7-Annulated Indoles from Indole-7-Carbaldehyde Derivatives and α,β-Unsaturated Aldehydes

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