53956-74-4

Basic information

• Product Name: GEO
• Synonyms: GEO;PENICILLIN-G-4-METHOXYBENZYL ESTER SULFOXIDE;PENICILLIN-G-P-METHOXYBENZYL ESTER SULFOXIDE
• CAS NO: 53956-74-4
• Molecular Formula: C₂₄H₂₆N₂O₆S
• Molecular Weight: 470.54
• Mol File: 53956-74-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: GEO(CAS DataBase Reference)
• NIST Chemistry Reference: GEO(53956-74-4)
• EPA Substance Registry System: GEO(53956-74-4)

Safety Data

• Hazardous Substances Data: 53956-74-4(Hazardous Substances Data)

Usage

General Description

The chemical compound "(4-Methoxyphenyl)methyl (2S,5R,6R)-3,3-dimethyl-4,7-dioxo-6-[(2-phenylacetyl)amino]-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate" is a complex organic molecule with a molecular formula C30H31NO6S. It consists of a 4-methoxyphenylmethyl group attached to a (2S,5R,6R)-3,3-dimethyl-4,7-dioxo-6-[(2-phenylacetyl)amino]-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate backbone. (4-Methoxyphenyl)methyl (2S,5R,6R)-3,3-dimethyl-4,7-dioxo-6-[(2-phenylacetyl)amino]-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is a derivative of a bicyclic amino acid and contains a phenylacetyl group. It is an ester derivative with potential pharmaceutical applications, potentially as a drug or pharmaceutical intermediate. The specific biological and pharmacological properties of this compound would need to be experimentally determined.

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 105-13-5 4-Methoxybenzyl alcohol 
• 30200-14-7 benzylpenicillin 4-methoxybenzyl ester 

Downstream Products

• 131903-39-4 1-<2-chloromethyl-1-(p-methoxybenzyloxycarbonyl)-2-propen-1-yl>-3-(phenylacetamido)-4-(phenylsulfonylthio)-2-azetidinone 
• 104146-10-3 (6R,7R)-3-Chloromethyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 

Relevant articles and documents

Preparation of 7-phenylacetamide-3-chloromethyl-cephalosporanic acid p-methoxybenzyl ester

The invention belongs to the field of synthesis of cephalosporin drug intermediates and disclosesa preparation method of 7-phenylacetamide-3-chloromethyl-cephalosporanic acid p-methoxybenzyl ester (short for GCLE). According to the method, penicillin G potassium salt taken as an initial raw material reacts with 4-methoxybenzylchloride firstly, penicillin sulfoxide ester is prepared through oxidation with peracetic acid and reacts with 2-mercaptobenzothiazole firstly, then a product reacts with benzene sulfinic acid, a ring opening product is obtained and reacts with chlorine, sodium methoxide is used for ring closing under the action of a methanol solvent, and 7-phenylacetamide-3-chloromethyl-cephalosporanic acid p-methoxybenzyl ester is obtained. The solvent is simple and easy to recover, reaction conditions are mild, operation is simple and convenient, and industrial production is easy.