5398-69-6

Basic information

• Product Name: 2-iodo-3-nitro-benzoic acid
• Synonyms: 2-Iodo-3-nitrobenzoicacid; NSC 4539
• CAS NO: 5398-69-6
• Molecular Formula: C₇H₄INO₄
• Molecular Weight: 293.02
• Mol File: 5398-69-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 207-212°C
• Boiling Point: 385.6°Cat760mmHg
• Flash Point: 187°C
• Appearance: /
• Density: 2.156g/cm³
• Vapor Pressure: 1.23E-06mmHg at 25°C
• Refractive Index: 1.702
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-iodo-3-nitro-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-3-nitro-benzoic acid(5398-69-6)
• EPA Substance Registry System: 2-iodo-3-nitro-benzoic acid(5398-69-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 5398-69-6(Hazardous Substances Data)

Usage

General Description

2-Iodo-3-nitro-benzoic acid is a chemical compound with the molecular formula C7H4INO5. It is a derivative of benzoic acid, containing a nitro group and an iodo group attached to the benzene ring. 2-iodo-3-nitro-benzoic acid is commonly used in organic synthesis and pharmaceutical research due to its potential as a building block for more complex molecules. It has also been studied for its antibacterial and anti-inflammatory properties, making it a potentially valuable compound for medicinal purposes. The presence of the iodo and nitro groups gives 2-iodo-3-nitro-benzoic acid useful reactivity, making it a versatile starting material for the synthesis of a wide range of organic compounds.

InChI:InChI=1/C7H4INO4/c8-6-4(7(10)11)2-1-3-5(6)9(12)13/h1-3H,(H,10,11)

Upstream product

• 606-18-8 3-nitroanthranilic acid 
• 95067-27-9 2-acetylamino-3-nitro-benzoic acid methyl ester 
• 88-67-5 2-Iodobenzoic acid 
• 603-11-2 3-nitrophthalic acid 
• 134-20-3 2-carbomethoxyaniline 
• 570-24-1 2-Methyl-6-nitroaniline 
• 59907-22-1 N-(2-methyl-6-nitrophenyl)acetamide 
• 90417-80-4 2-acetylamino-3-nitro-benzoic acid 

Downstream Products

• 123278-03-5 3-chloro-2-iodo-benzoic acid 
• 16676-99-6 2,3-diiodo-benzoic acid 
• 85600-30-2 3-amino-2-iodo-benzoic acid 
• 93415-79-3 methyl 2-iodo-3-nitrobenzoate 
• 51640-62-1 2-iodo-3-nitrobenzoyl chloride 
• 158616-08-1 (2-iodo-3-nitrophenyl)methanol 
• 73406-19-6 2-Benzylthio-3-nitrobenzoesaeure 
• 13421-12-0 3-Nitro-2-phenylsulfanyl-benzoic acid 
• 185223-42-1 (2-Iodo-3-nitro-phenyl)-carbamic acid tert-butyl ester 
• 189125-09-5 2-iodo-3-nitrobenzamide 
• 369652-64-2 2-[(1-methyl-1H-indazol-7-yl)amino]-3-nitrobenzoic acid 
• 369652-68-6 2-[1⁽³⁾H-benzimidazol-4-ylamino]-3-nitrobenzoic acid 
• 369652-62-0 2-(1H-indazol-7-ylamino)-3-nitrobenzoic acid 
• 369652-65-3 2-(1H-indazol-4-ylamino)-3-nitrobenzoic acid 

Relevant articles and documents

A new synthesis of 'push-pull' naphthalenes by condensation of nitro-2-methylbenzoate esters with dimethylacetamide dimethyl acetal

Whereas condensation of 2-methyl-3-nitrobenzoate esters with dimethylformamide dimethyl acetal gives 5-nitroisocoumarin, analogous condensation with dimethylacetamide dimethyl acetal proceeds via a different route, affording 1-methoxy-3-dimethylamino-5-ni

[Bis(trifluoroacetoxy)iodo]p-nitrobenzene and [bis(trifluoroacetoxy)iodo]pentafluorobenzene as lead reagents for the direct ring contraction of lactams to pyrrolidines

Two 3-iodanes, namely [bis(trifluoroacetoxy)iodo]p-nitrobenzene and [bis(trifluoroacetoxy)iodo]pentafluorobenzene, were used to effect the direct ring-contraction of lactams to pyrrolidines. Intense reaction optimization was necessary but only

Intriguing substituent effect in modified Hoveyda-Grubbs metathesis catalysts incorporating a chelating iodo-benzylidene ligand

A series of modified Hoveyda-Grubbs catalysts incorporating a chelating iodo-benzylidene ligand were prepared and characterized. The presence of electron-withdrawing ring substituents in the para position to the iodide was found to decrease the catalytic activity, revealing that dissociation of the Ru...I-Ar bond is not the rate-determining step.