539823-80-8 Usage
General Description
Pneumocandin A0 is a lipopeptide antibiotic and a natural product isolated from the fungus Glarea lozoyensis. It is of significant pharmaceutical interest due to its potent antifungal activity against a broad spectrum of fungal pathogens, including Candida and Aspergillus species. Pneumocandin A0 inhibits the synthesis of beta-glucan, an essential component of the fungal cell wall, by targeting the enzyme 1,3-beta-D-glucan synthase. This disruption in cell wall formation ultimately leads to the death of the fungal cells. Pneumocandin A0 has been used as the basis for the development of the antifungal drug caspofungin, which is used clinically for the treatment of invasive fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 539823-80-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,9,8,2 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 539823-80:
(8*5)+(7*3)+(6*9)+(5*8)+(4*2)+(3*3)+(2*8)+(1*0)=188
188 % 10 = 8
So 539823-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C56H71N9O19/c1-4-5-6-19-83-34-17-13-29(14-18-34)40-22-35(63-84-40)28-7-9-31(10-8-28)49(75)58-36-21-39(70)52(78)62-54(80)45-46(72)26(2)24-65(45)56(82)43(38(69)23-41(57)71)60-53(79)44(48(74)47(73)30-11-15-32(67)16-12-30)61-51(77)37-20-33(68)25-64(37)55(81)42(27(3)66)59-50(36)76/h7-18,22,26-27,33,36-39,42-48,52,66-70,72-74,78H,4-6,19-21,23-25H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)
