54011-33-5

Basic information

• Product Name: 3-BENZO[1,3]DIOXOL-5-YL-3-OXO-PROPIONIC ACID METHYL ESTER
• Synonyms: 3-BENZO[1,3]DIOXOL-5-YL-3-OXO-PROPIONIC ACID METHYL ESTER;BETA-OXO-1,3-BENZODIOXOLE-5-PROPANOIC ACID METHYL ESTER;methyl 3-(benzo[d][1,3]dioxol-5-yl)-3-oxopropanoate;Methyl b-oxo-1,3-benzodioxole-5-propanoate
• CAS NO: 54011-33-5
• Molecular Formula: C₁₁H₁₀O₅
• Molecular Weight: 222.19
• Mol File: 54011-33-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 346.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.317±0.06 g/cm3(Predicted)
• PKA: 10.74±0.20(Predicted)
• CAS DataBase Reference: 3-BENZO[1,3]DIOXOL-5-YL-3-OXO-PROPIONIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZO[1,3]DIOXOL-5-YL-3-OXO-PROPIONIC ACID METHYL ESTER(54011-33-5)
• EPA Substance Registry System: 3-BENZO[1,3]DIOXOL-5-YL-3-OXO-PROPIONIC ACID METHYL ESTER(54011-33-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 54011-33-5(Hazardous Substances Data)

Usage

General Description

3-Benzo[1,3]dioxol-5-yl-3-oxo-propionic acid methyl ester is a chemical compound with the molecular formula C11H10O5. It is a methyl ester of 3-benzo[1,3]dioxol-5-yl-3-oxo-propionic acid, and it is commonly used as a synthetic intermediate in organic chemistry. 3-BENZO[1,3]DIOXOL-5-YL-3-OXO-PROPIONIC ACID METHYL ESTER is a white solid that is sparingly soluble in water but soluble in organic solvents such as acetone and ethanol. Its primary use is in the production of pharmaceuticals and agrochemicals, where it serves as a building block for the synthesis of various organic compounds. It is important to handle this chemical with care, as it may be harmful if ingested, inhaled, or in contact with skin, and appropriate safety precautions should be taken when working with it.

Upstream product

• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 
• 616-38-6 carbonic acid dimethyl ester 
• 104548-23-4 4-acetoxy-3-methoxycarbonyl-4-(3,4-methylenedioxyphenyl)but-3-ene-2-one 
• 120-57-0 piperonal 
• 6832-16-2 methyl diazoacetate 
• 89447-03-0 2,5-dimethyl-4-(3,4-methylenedioxyphenyl)furan-3-carboxylic acid methylester 
• 25054-53-9 3,4-(methylenedioxy)benzoyl chloride 
• 38330-80-2 monomethyl monopotassium malonate 

Downstream Products

• 94671-07-5 methyl α-<(3,4,5-trimethoxyphenyl)methylene>-β-oxobenzo-1,3-dioxole-5-propanoate 
• 948904-78-7 C₁₉H₁₆O₆ 
• 948904-79-8 C₁₈H₁₄O₅ 
• 948904-80-1 C₁₉H₁₆O₅ 
• 124872-84-0 2-<(2'-hydroxy-4'-methoxy)phenoxy>-1-(3'',4''-methylenedioxyphenyl)-1,3-propanediol 
• 123913-96-2 3-Benzo[1,3]dioxol-5-yl-3-hydroxy-2-(2-hydroxy-4-methoxy-phenoxy)-propionic acid methyl ester 

Relevant articles and documents

Enantioselective decarboxylative Mannich reaction of β-keto acids withC-alkynylN-BocN,O-acetals: access to chiral β-keto propargylamines

The chiral keto-substituted propargylamines are an essential class of multifunctional compounds in the field of organic and pharmaceutical synthesis and have attracted considerable attention, but the related synthetic approaches remain limited. Therefore, a concise and efficient method for the enantioselective synthesis of β-keto propargylaminesviachiral phosphoric acid-catalyzed asymmetric Mannich reaction between β-keto acids andC-alkynylN-BocN,O-acetals as easily availableC-alkynyl imine precursors has been demonstrated here, affording a broad scope of β-ketoN-Boc-propargylamines in high yields (up to 97%) with generally high enantioselectivities (up to 97?:?3 er).

Novel cyclic phospholipids used for treating HCV infection

The invention relates to novel cyclic phospholipids, pharmaceutically acceptable salts or esters thereof and a medicine composition used for treating HCV infection. Chlorine in a phenyl ring of a Hepdirect cyclic phospholipid prodrug is replaced by a spec

Synthesis of β-Keto Esters Promoted by Yttria-Zirconia Based Lewis Acid Catalyst

A variety of aldehydes react with methyl/ethyl diazoacetate in the presence of yttria-zirconia based catalyst to afford the corresponding β-keto esters in excellent yields.