54011-41-5Relevant articles and documents
Azole endothelin antagonists. 1. A receptor model explains an unusual structure-activity profile
Von Geldern, Thomas W.,Hutchins, Charles,Kester, Jeffrey A.,Wu-Wong, Jinshyun R.,Chiou, William,Dixon, Douglas B.,Opgenorth, Terry J.
, p. 957 - 967 (2007/10/03)
The pseudotetrapeptide FR-139317 is a potent and highly selective antagonist of the endothelin-A (ET(A)) receptor; however, its peptidic nature leads to poor oral absorption characteristics which make it an unlikely drug candidate. In an attempt to improv
PHARMACOLOGICALLY ACTIVE GUANIDINE COMPOUNDS
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, (2015/12/08)
The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-guanidines which are inhibitors of histamine activity.
