5402-28-8

Basic information

• Product Name: 1,4-Dimethylcyclohexanol
• Synonyms: 1,4-Dimethylcyclohexanol;NSC 5100;1,4-Dimethyl-1-cyclohexanol
• CAS NO: 5402-28-8
• Molecular Formula: C₈H₁₆O
• Molecular Weight: 128.21204
• Mol File: 5402-28-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 174.3°Cat760mmHg
• Flash Point: 66.6°C
• Appearance: /
• Density: 0.903g/cm³
• Vapor Pressure: 0.377mmHg at 25°C
• Refractive Index: 1.456
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,4-Dimethylcyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dimethylcyclohexanol(5402-28-8)
• EPA Substance Registry System: 1,4-Dimethylcyclohexanol(5402-28-8)

Safety Data

• Hazardous Substances Data: 5402-28-8(Hazardous Substances Data)

Usage

General Description

1,4-Dimethylcyclohexanol is a colorless, oily liquid with a mild, camphor-like odor. It is an organic compound that is commonly used as a solvent in various chemical and industrial processes. Its molecular formula is C8H16O and it is derived from cyclohexane. The chemical has antiseptic and antibacterial properties, making it useful in the production of personal care products and pharmaceuticals. It is also utilized as an intermediate in the synthesis of other organic compounds. However, 1,4-Dimethylcyclohexanol is flammable and should be handled with caution.

InChI:InChI=1/C8H16O/c1-7-3-5-8(2,9)6-4-7/h7,9H,3-6H2,1-2H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 589-92-4 1-methylcyclohexan-4-one 
• 917-54-4 methyllithium 
• 74-88-4 methyl iodide 
• 104-93-8 p-methylanizole 
• 589-90-2 1,4 dimethylcyclohexane 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1073-15-0 1,4-dimethylcyclohexyl chloride 
• 2808-79-9 1,4-dimethylcyclohex-1-ene 
• 99799-35-6 1-bromo-1,4-dimethylcyclohexane 
• 589-90-2 1,4 dimethylcyclohexane 
• 932-51-4 2,5-dimethylcyclohexanone 
• 861538-31-0 1,4-dimethyl-cyclohexane-1,2-diol 
• 20237-24-5 1,2-dibromo-1,4-dimethyl-cyclohexane 

Relevant articles and documents

Heterogeneous Hydroxyl-Directed Hydrogenation: Control of Diastereoselectivity through Bimetallic Surface Composition

Directed hydrogenation, in which product selectivity is dictated by the binding of an ancillary directing group on the substrate to the catalyst, is typically catalyzed by homogeneous Rh and Ir complexes. No heterogeneous catalyst has been able to achieve equivalently high directivity due to a lack of control over substrate binding orientation at the catalyst surface. In this work, we demonstrate that Pd-Cu bimetallic nanoparticles with both Pd and Cu atoms distributed across the surface are capable of high conversion and diastereoselectivity in the hydroxyl-directed hydrogenation reaction of terpinen-4-ol. We postulate that the OH directing group adsorbs to the more oxophilic Cu atom while the olefin and hydrogen bind to adjacent Pd atoms, thus enabling selective delivery of hydrogen to the olefin from the same face as the directing group with a 16:1 diastereomeric ratio.

Restricted rotation due to the lack of free space within a capsule translates into product selectivity: Photochemistry of cyclohexyl phenyl ketones within a water-soluble organic capsule

The rotational mobility of organic guest molecules when included within a confined capsule is restricted and this feature could be translated into product selectivity as established with the photochemical behavior of cyclohexyl phenyl ketones. The Royal Society of Chemistry.

Functionalization of Saturated Hydrocarbons. Part 4. The Gif System for Selective Oxidation using Molecular Oxygen

Various systems for the selective oxidation of saturated hydrocarbons have been developed.These are based on the idea of an iron catalyst which is reduced by electron transfer and oxidized by molecular oxygen simultaneously in the presence of a source of protons.Four modifications of this system (the Gif system) have been devised of which the best (Gif IV) consists of an iron catalyst with metallic zinc as the reductant, acetic acid as the proton source and pyridine as the solvent.At room temperature, using oxygen or air, saturated hydrocarbons are oxidized selectively to ketones in isolated yields superior to those reported for comparable model systems.