540526-22-5Relevant articles and documents
Microwave enabled external carboxymethyl substituents in the ring-closing metathesis
Yang, Cangming,Murray, William V.,Wilson, Lawrence J.
, p. 1783 - 1786 (2003)
The ring-closing metathesis of diolefin substrates containing an external carboxymethyl substituent is presented. The reaction is enabled through microwave irradiation allowing greatly enhanced yields and conversion rates. The reaction results in the formation of carboxymethyl substituted dihydropyrroles, dihydrofurans, and cyclopentenes. In certain cases, pyrroles are formed through further in situ oxidation.
Practical one-pot sequential procedure for the preparation of N-arylated 3,4-disubstituted pyrroles from alkenes
Zhu, Rui,Xing, Lixin,Liu, Yantao,Deng, Fangkun,Wang, Xinyan,Hu, Yuefei
scheme or table, p. 3897 - 3901 (2009/04/07)
By using tBuONa and Cs2CO3 as a mixed base, van Leusen pyrrole synthesis and copper-catalyzed N-arylation of pyrrole proceeded sequentially in a single flask to give N-arylated 3,4-disubstituted pyrroles smoothly. Thus, a series of desired N-arylated pyrroles were prepared directly from the electron-deficient alkenes.
