540721-69-5

Basic information

• Product Name: (5R)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-1-{4-[(triisopropylsilyl)thio]butyl}-pyrrolidin-2-one
• Synonyms: (5R)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-1-{4-[(triisopropylsilyl)thio]butyl}-pyrrolidin-2-one
• CAS NO: 540721-69-5
• Molecular Weight: 475.811
• Mol File: 540721-69-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5R)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-1-{4-[(triisopropylsilyl)thio]butyl}-pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-1-{4-[(triisopropylsilyl)thio]butyl}-pyrrolidin-2-one(540721-69-5)
• EPA Substance Registry System: (5R)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-1-{4-[(triisopropylsilyl)thio]butyl}-pyrrolidin-2-one(540721-69-5)

Safety Data

• Hazardous Substances Data: 540721-69-5(Hazardous Substances Data)

Upstream product

• 540721-68-4 (5R)-1-(4-chlorobutyl)-5-[(1E)-3-oxo-4-phenylbut-1-enyl]pyrrolidin-2-one 
• 540721-65-1 (5R)-({[tert-butyl-(dimethyl)sylanyl]oxy}methyl)-1-(4-chlorobutyl)pyrrolidin-2-one 
• 540721-66-2 (5R)-1-(4-chlorobutyl)-5-(hydroxymethyl)pyrrolidin-2-one 
• 540721-67-3 (2R)-1-(4-chlorobutyl)-5-oxopyrrolidine-2-carboxaldehyde 
• 128899-30-9 (R)-5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one 
• 156275-96-6 triisopropylsilanethiol 
• 540721-64-0 (5R)-1-(4-chlorobutyl)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-pyrrolidin-2-one 

Downstream Products

• 540721-60-6 [(4-{(2R)-2-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl}butyl)thio]methanesulfonic acid 
• 540721-71-9 (5R)-5-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-1-[4-(methylthio)butyl]pyrrolidin-2-one 
• 540721-72-0 [(4-{(2R)-2-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl}butyl)thio]acetonitrile 

Relevant articles and documents

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This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the