54089-05-3

Basic information

• Product Name: 2-Pyridinecarboxamide,4-cyano-(9CI)
• Synonyms: 2-Pyridinecarboxamide,4-cyano-(9CI);4-Cyano-2-pyridinecarboxamide;2-amido-4-cyanopyridine
• CAS NO: 54089-05-3
• Molecular Formula: C₇H₅N₃O
• Molecular Weight: 147.1341
• Product Categories: AMIDE
• Mol File: 54089-05-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinecarboxamide,4-cyano-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxamide,4-cyano-(9CI)(54089-05-3)
• EPA Substance Registry System: 2-Pyridinecarboxamide,4-cyano-(9CI)(54089-05-3)

Safety Data

• Hazardous Substances Data: 54089-05-3(Hazardous Substances Data)

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 77287-34-4 formamide 
• 108-75-8 2,4,6-trimethyl-pyridine 

Downstream Products

• 499-80-9 pyridine-2,4-dicarboxylic acid 

Relevant articles and documents

Transition-metal-free synthesis of primary to tertiary carboxamides: A quick access to prodrug-pyrazinecarboxamide

One-pot expedient and direct carbamoylation of heterocyclics is described. The transformation is realized via direct dehydrogenative aminocarbonylation of heterocyclic compounds under transition-metal-free conditions. This method is regioselective and the protocol is proved to be scalable on a gram scale. Further, the therapeutically useful antitubercular agent pyrazinecarboxamide is successfully synthesized by employing this protocol.

Oxidative ammonolysis of 2,4,6-collidine at vanadium-titanium oxide catalyst

4-Cyanopyridine was synthesized from the readily obtainable 2,4,6-collidine by oxidative ammonolysis in the presence of vanadium-titanium oxide catalyst. Conditions under which the yield of the product amounted to 73% on the amount of the trimethylpyridin

Process for the preparation of 2,4-pyridine dicarboxylic acid

A process for the preparation of carboxamides of nitrogen-containing aromatic heterocyclic compounds from the corresponding N-heterocyclic compounds by reaction thereof with formamide in the presence of peroxodisulfuric acid or a peroxodisulfate.