54093-92-4 Usage
Description
6-Des(diethanolamino)-6-chloro Dipyridamole, also known as Dipyridamole EP Impurity C, is a derivative of Dipyridamole (D492625) with potential antitumor properties. It is characterized by the absence of a diethanolamino group and the presence of a chloro group at the 6th position, which may contribute to its unique biological activities.
Uses
Used in Pharmaceutical Industry:
6-Des(diethanolamino)-6-chloro Dipyridamole is used as an impurity in the synthesis of Dipyridamole, a medication used to prevent blood clots and treat certain heart conditions. Its presence as an impurity may affect the efficacy and safety of the final product, making it important to monitor and control its levels during the manufacturing process.
Used in Anticancer Applications:
6-Des(diethanolamino)-6-chloro Dipyridamole is used as an antitumor agent due to its potential to inhibit the growth of cancer cells. As a pyrimido pyrimidine nucleoside, it may interfere with the replication and transcription processes of cancer cells, leading to their death. Further research is needed to fully understand its mechanism of action and potential applications in cancer treatment.
Used in Drug Development:
6-Des(diethanolamino)-6-chloro Dipyridamole may be used as a starting point for the development of new antitumor drugs. Its unique chemical structure and potential antitumor activity make it an interesting candidate for further investigation and optimization to improve its efficacy and selectivity towards cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 54093-92-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,0,9 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54093-92:
(7*5)+(6*4)+(5*0)+(4*9)+(3*3)+(2*9)+(1*2)=124
124 % 10 = 4
So 54093-92-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H30ClN7O2/c21-19-22-15-16(17(24-19)26-7-3-1-4-8-26)23-20(28(11-13-29)12-14-30)25-18(15)27-9-5-2-6-10-27/h29-30H,1-14H2
54093-92-4Relevant articles and documents
PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE
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Page/Page column 19, (2011/12/14)
The present invention relates to the active pharmaceutical ingredient dipyridamole. In particular, it relates to efficient processes for the preparation of dipyridamole which are amenable to large scale commercial production and provide the required product with improved yield and purity. The present invention also relates to a novel crystallization method for the purification of dipyridamole.