54117-67-8Relevant articles and documents
Diversity oriented approach to polycyclic compounds through the diels-alder reaction and the Suzuki coupling
Kotha, Sambasivarao,Misra, Shilpi,Srinivas, Venu
scheme or table, p. 4052 - 4062 (2012/09/07)
A diversity oriented strategy has been demonstrated to deliver small "drug like" molecules using alkylation, Diels-Alder reaction, and Suzuki-Miyaura cross-coupling as key steps. This methodology allows access a wide range of molecules using simple scaffolds such as indanes, tetralins and tetrahydroisoquinolines, which can enhance the chemical space for potential therapeutic molecules.
Studies on the Chemistry of Isoindoles and Isoindolenines, XXXVII. - Symmetrically Substituted 2-Alkyl-2H-isoindoles
Kreher, Richard P.,Sewarte-Ross, Guenter,Vogt, Guenther
, p. 1719 - 1727 (2007/10/02)
2-Alkyl-Rn-2H-isoindoles (1; Rn = 4,5,6,7-tetramethyl, 4,5,6,7-tetrachloro) have been prepared efficiently by the N-oxide route and characterized by spectroscopic means.
Isoindolinyl derivatives
-
, (2008/06/13)
Esters of lower alkanoic acids substituted at the α-position with isoindoline or tetrahydroisoquinoline, and intermediates therefor, useful as pesticides.