5413-96-7

Basic information

• Product Name: 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine
• Synonyms: 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine;6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;4-chloro-1;6-chloro-1-Methylpyrazolo[3,4-d]pyriMidin-4-aMine;6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
• CAS NO: 5413-96-7
• Molecular Formula: C7H7ClN4
• Molecular Weight: 182.61028
• Mol File: 5413-96-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.79g/cm³
• Refractive Index: 1.821
• CAS DataBase Reference: 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine(5413-96-7)
• EPA Substance Registry System: 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine(5413-96-7)

Safety Data

• Hazardous Substances Data: 5413-96-7(Hazardous Substances Data)

Usage

Description

4-Chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine is a heterocyclic chemical compound with the molecular formula C7H7ClN4. It features a pyrazolopyrimidine skeleton and is widely recognized as a valuable building block in the synthesis of pharmaceuticals and agrochemicals.

Uses

Used in Pharmaceutical Industry:
4-Chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine is utilized as a key intermediate in the development of new drugs for various medical treatments. Its unique structure and properties make it a promising candidate for the creation of innovative therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 4-chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine is employed as a component in the formulation of pesticides, fungicides, and herbicides. Its incorporation enhances the effectiveness of these products, contributing to improved crop protection and yield.
Used in Research and Development:
4-Chloro-1,6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine is a compound of significant interest to researchers and scientists in the fields of chemistry, pharmacology, and agriculture. Its versatility and potential applications make it a valuable subject for ongoing studies aimed at uncovering new uses and refining existing ones.

InChI:InChI=1/C6H6ClN5/c1-12-5-3(2-9-12)4(8)10-6(7)11-5/h2H,1H3,(H2,8,10,11)

Upstream product

• 98141-42-5 4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 
• 5401-15-0 1-Methyl-1H-pyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dione 
• 5334-41-8 5-amino-4-cyano-1-methylpyrazole 
• 50270-27-4 2,4,6-trichloropyrimidine-5-carbaldehyde 

Downstream Products

• 5444-33-7 2-(4-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)-ethanol 
• 5399-91-7 6-amino-1-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one 
• 91843-67-3 1-methyl-6-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 

Relevant articles and documents

PYRIMIDINE AMIDE COMPOUNDS AND USE THEREOF

Disclosed are compounds of formula (I) below or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof: (I), in which each of variables each of variables R, R1, R2, X1, X2, X3 and n is defined herein. Also disclosed is a method for treating a cancer with a compound of formula (I) or a salt thereof and a pharmaceutical composition containing same.

2-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS

The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.