5415-06-5 Usage
Description
1-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-hydroxyethanone, also known as clevidence or nocapone, is a chemical compound with the molecular formula C16H13ClO4. It is a potent inhibitor of catechol-O-methyltransferase (COMT), an enzyme involved in the breakdown of neurotransmitters such as dopamine, epinephrine, and norepinephrine. 1-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-hydroxyethanone has been studied for its potential therapeutic applications, particularly in the treatment of Parkinson's disease, due to its ability to increase dopamine levels in the brain. It also exhibits antioxidant and anti-inflammatory properties, although further research is necessary to fully understand its therapeutic potential and any potential side effects.
Uses
Used in Pharmaceutical Industry:
1-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-hydroxyethanone is used as a therapeutic agent for the treatment of Parkinson's disease. Its application is based on its ability to inhibit the COMT enzyme, which results in increased levels of dopamine in the brain, thereby potentially alleviating the symptoms of Parkinson's disease.
Used in Research and Development:
1-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-hydroxyethanone is used as a research compound for studying the role of COMT inhibition in the treatment of neurological disorders and for exploring its antioxidant and anti-inflammatory properties. This application aids in the development of new therapeutic strategies and understanding the underlying mechanisms of various diseases.
Used in Chemical Synthesis:
1-(1,3-benzodioxol-5-yl)-2-(4-chlorophenyl)-2-hydroxyethanone may also be used as a synthetic intermediate in the development of new chemical compounds with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals. Its unique structure and functional groups make it a valuable building block for the synthesis of novel molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5415-06-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,1 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5415-06:
(6*5)+(5*4)+(4*1)+(3*5)+(2*0)+(1*6)=75
75 % 10 = 5
So 5415-06-5 is a valid CAS Registry Number.
5415-06-5Relevant articles and documents
Synthesis of chiral α-diarylacetic esters by stereospecific 1,2-aryl migration promoted by in situ generated acetals from benzoins
Kothapalli, Raveendra Babu,Niddana, Ramana,Balamurugan, Rengarajan
, p. 1278 - 1281 (2014/04/03)
A simple protocol for the synthesis of α-diarylacetic esters from benzoins is described. In situ generated acetal assists rapid 1,2-aryl migration in a stereospecific manner, paving the way to make enantioenriched α-diarylacetic esters from easily accessi
