54166-25-5

Basic information

• Product Name: (E)-1,8-diamino-p-menthane
• Synonyms: (E)-1,8-diamino-p-menthane
• CAS NO: 54166-25-5
• Molecular Weight: 170.298
• Mol File: 54166-25-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-1,8-diamino-p-menthane(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,8-diamino-p-menthane(54166-25-5)
• EPA Substance Registry System: (E)-1,8-diamino-p-menthane(54166-25-5)

Safety Data

• Hazardous Substances Data: 54166-25-5(Hazardous Substances Data)

Upstream product

• 127322-88-7 trans-N-(2-(4-acetamido-4-methylcyclohexyl)propan-2-yl)acetamide 
• 58940-69-5 (E)-1,8-dinitro-p-menthane 

Relevant articles and documents

Turpentine Derived Secondary Amines for Sustainable Crop Protection: Synthesis, Activity Evaluation and QSAR Study

In this study, we will report on the synthesis and application of efficient botanical agrochemicals from turpentine for sustainable crop protection. Two series of turpentine derived secondary amines were synthesized and identified by FT-IR, 1H NMR, 13C NMR, and HRMS. The herbicidal activities against Echinochloa crus-galli were evaluated. The potential toxicity of the synthesized compounds was tested by MTT cytotoxicity analysis. The effect of structure of the synthesized secondary amines and corresponding Schiff base compounds on their activities was investigated by quantitative structure-activity relationship (QSAR) study. All target products were found to be low toxicity, with similar or higher herbicidal activities than commercial herbicides diuron and Glyphosate. Results of QSAR study showed that a best four-descriptor QSAR model with R2 of 0.880 and Rloo2 of 0.818 was obtained. The four descriptors most relevant to the herbicidal activities are the min valency of a N atom, the max total interaction for a C-H bond, the relative number of aromatic bonds, and the min partial charge (Qmin).