5424-20-4 Usage
Description
Tannic Acid, also known as gallotannin, is a polyphenol of gallic acid derived from hydrolyzable tannins found in various plant sources such as gall nuts, bark of trees, oak galls, and tea. It possesses weak acidic properties, a strong astringent taste, and has antioxidant, anti-inflammatory, antiviral, and antiproliferative biological activities. Its hydroxy and carboxy groups enable interactions with biopolymers and macromolecules, making it a promising pharmaceutical candidate for various applications.
Uses
Used in Anticancer Applications:
Tannic Acid is used as an anticancer agent for its ability to modulate several oncological signaling pathways, including JAK/STAT, RAS/RAF/mTOR, TGF-β1/TGF-β1R, VEGF/VEGFR, and CXCL12/CXCR4 axes. It exerts inhibitory effects on tumor growth and progression, particularly against solid malignancies such as liver, breast, lung, pancreatic, colorectal, and ovarian cancers. Additionally, Tannic Acid demonstrates synergistic anticancer effects when combined with conventional chemotherapeutic drugs, enhancing chemo-sensitivity and efficacy in resistant cases.
Used in Drug Delivery Systems:
Tannic Acid is used in the development of novel drug delivery systems to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles have been employed as carriers for Tannic Acid delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.
Used in Tanning Industry:
Tannic Acid is used as a tanning agent for tanning animal skins to make leather. It is also used as a mordant in dyeing, providing a means to bond dye to fabric more effectively.
Used in Leather Production:
Tannic Acid is used in the production of leather, where it helps in the tanning process by causing the skin to contract and harden, making it more durable and resistant to decay.
Used in Ink and Dye Production:
Tannic Acid is used in the production of inks and dyes, particularly for making dyes and inks from plant sources. It serves as a mordant, which helps to bond the dye to the fabric more effectively.
Check Digit Verification of cas no
The CAS Registry Mumber 5424-20-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,2 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5424-20:
(6*5)+(5*4)+(4*2)+(3*4)+(2*2)+(1*0)=74
74 % 10 = 4
So 5424-20-4 is a valid CAS Registry Number.
InChI:InChI=1/C76H52O46/c77-32-1-22(2-33(78)53(32)92)67(103)113-47-16-27(11-42(87)58(47)97)66(102)112-21-52-63(119-72(108)28-12-43(88)59(98)48(17-28)114-68(104)23-3-34(79)54(93)35(80)4-23)64(120-73(109)29-13-44(89)60(99)49(18-29)115-69(105)24-5-36(81)55(94)37(82)6-24)65(121-74(110)30-14-45(90)61(100)50(19-30)116-70(106)25-7-38(83)56(95)39(84)8-25)76(118-52)122-75(111)31-15-46(91)62(101)51(20-31)117-71(107)26-9-40(85)57(96)41(86)10-26/h1-20,52,63-65,76-101H,21H2/t52-,63-,64+,65-,76+/m1/s1
5424-20-4Relevant articles and documents
Complexating systems, intermediates for their production and method for obtaining and using the same
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, (2008/06/13)
The present invention is related to a complexating system comprising a tannin immobilised on a solid support by means of a bifunctional spacer which is covalently bound from one hand to said solid support by a first function and from the other hand to said tannin by a second function, wherein the tannin is a naturally occurring tannin and exhibits at least six hydroxyl groups. Said complexating system can be used in particular for chelating metals and proteins, as an antioxidant, as a radical scavenger or as an antibacterial. More specifically, applications can be found in the clarification and stabilisation of beverages, the treatment of textiles, or the separation and/or purification of proteins and/or metals.